Pavarin Raimondo Maria, Sanchini Samantha, Tadonio Leonardo, Domenicali Marco, Caputo Fabio, Pacetti Monica
Epidemiological Monitoring Center on Addiction, Azienda USL Bologna, Mental Health DSM-DP, Bologna, Italy; Italian Society on Addiction (SITD);.
Epidemiological Monitoring Center on Addiction, Mental Health DSM-DP, Azienda USL Romagna, Italy.
Psychiatry Res. 2021 Feb;296:113639. doi: 10.1016/j.psychres.2020.113639. Epub 2020 Dec 11.
Cohort study. This follow-up study (from 1975 to 2016) was aimed to estimate the mortality risk for suicide in a cohort of patients presenting to a public treatment centre for addiction (SERD) with Alcohol Use Disorder (AUD), Heroin Use Disorder - HUD or Cocaine Use Disorder (CUD), also relating to their access to a Mental Heath Service. Crude Mortality Rates for suicide were higher for patients with AUDs, for men and subjects 45-64 years old. Hanging was the main cause of suicide death. We highlight an increase in mortality in the period 2009-2012, which coincides with the economic recession, and in the year of first contact with a SERD. The Standardized Mortality Ratios (SMRs) were 4.9, higher among females than males. From the multivariate analysis, a higher risk for patients that were separated or divorced was observed. The results of our study provide some guidance on the features of subjects at greatest risk of death from suicide, which may be useful in reducing and preventing suicide and gaining a better clinical management of patients with SUDs.
队列研究。这项随访研究（1975年至2016年）旨在评估在一家公共成瘾治疗中心（SERD）就诊的患有酒精使用障碍（AUD）、海洛因使用障碍（HUD）或可卡因使用障碍（CUD）的患者队列中的自杀死亡风险，同时研究其获得心理健康服务的情况。AUD患者、男性以及45 - 64岁的受试者自杀的粗死亡率较高。上吊是自杀死亡的主要原因。我们强调在2009 - 2012年期间死亡率有所上升，这与经济衰退以及首次接触SERD的年份相吻合。标准化死亡比（SMR）为4.9，女性高于男性。多变量分析显示，分居或离婚的患者自杀风险更高。我们的研究结果为自杀死亡风险最高的人群特征提供了一些指导，这可能有助于减少和预防自杀，并更好地对物质使用障碍患者进行临床管理。
