Vaccine Research Program, Division of AIDS, National Institute of Allergy and Infectious Diseases, 5601 Fishers Lane, Rm 9C20B, Bethesda, MD 20892-9829, USA.
Viruses. 2020 Dec 19;12(12):1469. doi: 10.3390/v12121469.
Funding vaccine development research is more complicated than simply putting out an announcement of funds available. The funders must decide whether product development can be accomplished by purely applied research, or whether more fundamental knowledge is needed before product development can be started. If additional basic knowledge is needed, identifying the specific area of the knowledge gap can be a challenge. Additionally, when there appears to be a clear path of applied research sometimes obstacles are encountered that require a return to more basic work. After deciding on the work to be done, funders must attract the scientists with the broad range of needed skills to cover all the stages of development. Collaborations must be promoted and alliances with other funders and industry must be developed. Funders use multiple tools and strategies to accomplish these tasks with varying success.
资助疫苗研发比单纯发布可用资金的公告要复杂得多。资助者必须决定产品开发是可以通过纯粹的应用研究来完成，还是在开始产品开发之前需要更多的基础知识。如果需要更多的基础知识，那么确定知识差距的具体领域可能是一个挑战。此外，当看起来有明确的应用研究路径时，有时会遇到需要回到更基础工作的障碍。在决定要做的工作后，资助者必须吸引具有广泛所需技能的科学家来覆盖所有的开发阶段。必须促进合作，并与其他资助者和行业建立联盟。资助者使用多种工具和策略来完成这些任务，但取得的成功程度不同。
