Ophthalmology Clinic, Ulucanlar Eye Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Eur J Ophthalmol. 2021 Nov;31(6):3177-3181. doi: 10.1177/1120672120983169. Epub 2020 Dec 22.
To investigate the effect of ocular dominance on pattern electroretinogram (PERG) recordings in the participants who have no ophthalmic diseases.
One hundred and twelve eyes of 56 participants (mean age 32.96 ± 10.82 years) were included in this prospective, cross-sectional study. After detailed ophthalmological examination and determination of the ocular dominance with hole-in-a-card test, the PERG was performed to determine implicit time and amplitudes of P50 and N95.
There were no significant interocular differences in visual acuity, refractive error, or intraocular pressure ( > 0.05 for all). Thirty-six (64.3%) of the participants had ocular dominance in the right eye. The dominant eyes had significantly higher P50 amplitude than in the fellow nondominant eyes (6.90 µV in dominant vs 5.87 µV in nondominant; = 0.015; 95% confidence interval). There was no significant difference in N95 amplitude, N95/P50 ratio, and implicit times of P50 and N95 between the dominant and nondominant eyes of the participants ( = 0.090, = 0.124 = 0.817, = 0.668; respectively).
The analysis revealed a significantly increased P50 amplitude of the PERG, which is known to be highly associated with macular function, in dominant eyes of the patients when compared to fellow nondominant eyes.
研究无眼部疾病的参与者的眼优势对视锥细胞层视网膜电流图（PERG）记录的影响。
本前瞻性、横断面研究纳入了 56 名参与者的 112 只眼（平均年龄 32.96±10.82 岁）。在进行详细的眼科检查并通过孔板试验确定眼优势后，进行 PERG 以确定 P50 和 N95 的潜伏期和振幅。
参与者的视力、屈光不正或眼压在双眼间均无显著差异（均>0.05）。36 只眼（64.3%）为右眼优势眼。主导眼的 P50 振幅明显高于对侧非主导眼（主导眼 6.90µV，非主导眼 5.87µV； = 0.015；95%置信区间）。参与者主导眼和非主导眼的 N95 振幅、N95/P50 比值以及 P50 和 N95 的潜伏期均无显著差异（ = 0.090， = 0.124 = 0.817， = 0.668；分别）。
与对侧非主导眼相比，患者主导眼的 PERG 的 P50 振幅明显增加，而 P50 振幅与黄斑功能高度相关。
