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COVID-19 大流行期间的输血实践:来自印度血液科日间病房的经验。

Transfusion practices during the COVID-19 pandemic: An experience from a hematology daycare in India.

机构信息

Department of Hematology, AIIMS, New Delhi, 110029, India.

Haematology Day Care, AIIMS, New Delhi, 110029, India.

出版信息

Transfus Apher Sci. 2021 Apr;60(2):103025. doi: 10.1016/j.transci.2020.103025. Epub 2020 Nov 26.

Abstract

The Coronavirus disease-19 (COVID-19) pandemic has in multiple ways affected healthcare delivery to non-COVID patients throughout the world. Adequate transfusion services are fundamental in ongoing therapy of patients with hematological ailments. We present the transfusion services in the hematology daycare under the department of Hematology and supported by the Blood Bank at our institution for the period 12th April 2020-30th June 2020, which saw the stringent lockdown and unlocking Phase I in India, declared in lieu of the pandemic. A 56 % reduction in total transfusion sessions was observed in 2020 (588 sessions given to 176 patients) compared to 1336 sessions in 516 patients over the same period in 2019. The reductions were seen across the different blood components (packed red blood cells [PRBC]: 585 vs. 1840, platelet rich plasma: 372 vs. 1313, single donor platelet 18 vs. 16), with a significant reduction in the mean PRBC transfused per PRBC transfusion session (1.11 vs 1.99, p<0.001) in 2020, compared to 2019. There were however no major differences in the transfusion practices across the different phases of the lockdown. Our study highlights the detrimental reduction in transfusion services due to the COVID-19 pandemic and related lockdown and showcases the remedial strategies taken to maximize transfusion support to patients during this period. Our observations might help to provide insights to adequately combat possible similar adverse situations in the future.

摘要

新型冠状病毒病-19(COVID-19)大流行以多种方式影响了全球非 COVID 患者的医疗服务提供。充足的输血服务是血液病患者持续治疗的基础。我们介绍了在血液病日间病房提供的输血服务,该病房由血液病科支持,并由我们机构的血库提供。该时段为 2020 年 4 月 12 日至 6 月 30 日,恰逢印度宣布严格封锁和第一阶段解锁,以应对疫情。与 2019 年同期的 516 名患者接受 1336 次输血相比,2020 年的总输血次数减少了 56%(176 名患者接受 588 次输血)。不同血液成分(浓缩红细胞[PRBC]:585 与 1840,富含血小板的血浆:372 与 1313,单供体血小板:18 与 16)的输血次数均有所减少,与 2019 年相比,PRBC 输血次数中每单位 PRBC 输血的平均 PRBC 输血量显著减少(1.11 与 1.99,p<0.001)。但是,在封锁的不同阶段,输血实践没有太大差异。我们的研究强调了 COVID-19 大流行及相关封锁导致的输血服务减少,并展示了在此期间为最大程度地支持患者而采取的补救策略。我们的观察结果可能有助于为将来可能出现的类似不良情况提供足够的应对措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80b8/7690339/ceed0848cbf0/gr1_lrg.jpg

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