Makarenko Vladislav V, Kandil Dina, Cosar Ediz F, Hutchinson Lloyd, Khan Ashraf
Department of Pathology, University of Massachusetts Memorial Medical Center, Worcester, MA, USA.
Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
Rare Tumors. 2020 Dec 9;12:2036361320979219. doi: 10.1177/2036361320979219. eCollection 2020.
Primary peritoneal serous carcinomas (PPSC) are exceedingly rare in male patients. Only a few cases were reported, and mostly with the limited immunophenotypical characterization. No molecular analysis of PPSC in males has been previously performed. We here describe another case of PPSC in a male patient. A comprehensive molecular analysis of the tumor revealed SF3B1 gene mutation as a possible driver.
原发性腹膜浆液性癌（PPSC）在男性患者中极为罕见。仅有少数病例被报道，且大多免疫表型特征有限。此前尚未对男性PPSC进行分子分析。我们在此描述另一例男性PPSC患者。对该肿瘤进行的全面分子分析显示，SF3B1基因突变可能是驱动因素。
