Kamura Takuro, Tanaka Yuhei, Tsumura Naoya, Ohya Takashi, Okamatsu Yuki
Department of Pediatrics, Aso Iizuka Hospital, 3-83 Yoshio Town, Iizuka 820-8505, Japan.
Department of Pediatrics and Child Health, Kurume University School of Medicine, 67 Asahi Town, Kurume 830-0011, Japan.
Case Rep Pediatr. 2020 Nov 27;2020:8846511. doi: 10.1155/2020/8846511. eCollection 2020.
() infection complicated with bacteremia rarely occurs. infection is also known to produce various symptoms similar to Kawasaki disease (KD) due to the production of -derived mitogen (YPM), an exotoxin with superantigen activity. Moreover, it causes terminal ileitis and is responsible for appendix swelling. Here, we report a case of infection in a 10-month-old boy who was brought to our hospital due to fever, watery stool, and poor vitality. Abdominal echocardiography revealed wall thickening of the entire colon and appendix swelling; therefore, he was admitted and treated with antibiotics for bacterial enteritis or appendicitis. After the antibiotic administration, facial skin rashes and hand and foot edema developed. However, he had 5/6 major symptoms of KD and was diagnosed with infection because of its presence in the blood and stool cultures. Thereafter, antibacterial therapy improved his symptoms and increased the inflammatory response. After his hospital discharge, the skin on his fingers showed desquamation like that of KD. infection should be considered as a differential disease in KD, terminal ileitis, and appendicitis. Furthermore, its infection route and culture methods should also be carefully considered.
()感染合并菌血症很少发生。已知该感染会因产生具有超抗原活性的外毒素——衍生有丝分裂原(YPM)而产生各种类似于川崎病(KD)的症状。此外,它会导致末端回肠炎并引起阑尾肿胀。在此,我们报告一例10个月大男孩的()感染病例,该男孩因发热、水样便和活力不佳被带到我院。腹部超声心动图显示整个结肠壁增厚和阑尾肿胀;因此,他入院并接受抗生素治疗以治疗细菌性肠炎或阑尾炎。抗生素给药后,出现面部皮疹和手足水肿。然而,他有5/6项KD主要症状,且由于血液和粪便培养中存在()而被诊断为()感染。此后,抗菌治疗改善了他的症状并增加了炎症反应。出院后,他手指上的皮肤出现了类似KD的脱皮现象。在KD、末端回肠炎和阑尾炎中,应将()感染视为鉴别疾病。此外,还应仔细考虑其感染途径和培养方法。