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1
Carisoprodol Abuse in Adolescence.青少年中的卡立普多滥用问题。
Cureus. 2020 Nov 17;12(11):e11525. doi: 10.7759/cureus.11525.
2
Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone.急性下腰痛常用的肌肉松弛剂疗法:卡立普多、盐酸环苯扎林和美他沙酮的综述
Clin Ther. 2004 Sep;26(9):1355-67. doi: 10.1016/j.clinthera.2004.09.008.
3
Carisoprodol (soma): abuse potential and physician unawareness.卡立普多(索马):滥用潜力与医生的忽视
J Addict Dis. 1999;18(2):51-6. doi: 10.1300/J069v18n02_05.
4
Carisoprodol as a drug of abuse.
Arch Fam Med. 1993 Apr;2(4):429-32. doi: 10.1001/archfami.2.4.429.
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Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose.14年成瘾及急性过量服用后出现的严重卡立普多戒断反应
J Emerg Med. 2017 May;52(5):680-683. doi: 10.1016/j.jemermed.2016.11.015. Epub 2016 Dec 12.
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Carisoprodol: a drug of continuing abuse.卡立普多:一种持续被滥用的药物。
J Am Osteopath Assoc. 1997 Dec;97(12):723-4. doi: 10.7556/jaoa.1997.97.12.723.
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Impairment due to intake of carisoprodol.因服用卡立普多导致的损伤。
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本文引用的文献

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A Comparison of Screening Practices for Adolescents in Primary Care After Implementation of Screening, Brief Intervention, and Referral to Treatment.《实施筛查、简短干预和转介治疗后,初级保健中青少年的筛查实践比较》
J Adolesc Health. 2019 Jul;65(1):46-50. doi: 10.1016/j.jadohealth.2018.12.005. Epub 2019 Mar 6.
2
Childhood Psychiatric Disorders as Risk Factor for Subsequent Substance Abuse: A Meta-Analysis.儿童期精神障碍是随后物质滥用的风险因素:一项荟萃分析。
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Multisystemic Therapy for Externalizing Youth.针对外化问题青少年的多系统治疗
Child Adolesc Psychiatr Clin N Am. 2015 Jul;24(3):601-16. doi: 10.1016/j.chc.2015.02.007. Epub 2015 Mar 29.
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Carisoprodol: update on abuse potential and legal status.卡立普多:滥用潜力与法律地位的最新情况。
South Med J. 2012 Nov;105(11):619-23. doi: 10.1097/SMJ.0b013e31826f5310.
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Carisoprodol: abuse potential and withdrawal syndrome.卡立普多:滥用潜力与戒断综合征。
Curr Drug Abuse Rev. 2010 Mar;3(1):33-8. doi: 10.2174/1874473711003010033.
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Prescription of nonsteroidal anti-inflammatory drugs and muscle relaxants for back pain in the United States.美国非甾体抗炎药和肌肉松弛剂用于背痛的处方情况。
Spine (Phila Pa 1976). 2004 Dec 1;29(23):E531-7. doi: 10.1097/01.brs.0000146453.76528.7c.
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Validity of the CRAFFT substance abuse screening test among adolescent clinic patients.青少年门诊患者中CRAFFT药物滥用筛查测试的效度
Arch Pediatr Adolesc Med. 2002 Jun;156(6):607-14. doi: 10.1001/archpedi.156.6.607.
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Prevalence of adolescent substance use disorders across five sectors of care.五个医疗领域中青少年物质使用障碍的患病率。
J Am Acad Child Adolesc Psychiatry. 2001 Apr;40(4):419-26. doi: 10.1097/00004583-200104000-00010.
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Risk for substance use disorders in youths with child- and adolescent-onset bipolar disorder.患有儿童及青少年期双相情感障碍的青少年出现物质使用障碍的风险。
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Adolescent psychopathology: I. Prevalence and incidence of depression and other DSM-III-R disorders in high school students.青少年精神病理学:I. 高中生中抑郁症及其他《精神疾病诊断与统计手册》第三版修订本(DSM-III-R)所定义疾病的患病率与发病率
J Abnorm Psychol. 1993 Feb;102(1):133-44. doi: 10.1037//0021-843x.102.1.133.

青少年中的卡立普多滥用问题。

Carisoprodol Abuse in Adolescence.

作者信息

Gupta Mayank

机构信息

Psychiatry, Clarion Psychiatric Center, Clarion, USA.

出版信息

Cureus. 2020 Nov 17;12(11):e11525. doi: 10.7759/cureus.11525.

DOI:10.7759/cureus.11525
PMID:33354469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7746313/
Abstract

Carisoprodol (i.e. Soma, Soprodol, Vanadom) is a muscle relaxant prescribed to relieve symptoms of muscle pain. Carisoprodol's addiction potential in adults has been well-established through case reports in the past. Carisoprodol abuse in adolescents has been reported in the 'Monitoring the Future' study since 2007, but no case studies or research has been published to date. Due to its relatively short half-life, tolerance and dependence develop quite quickly, leading to negative mental health outcomes. Awareness and education among health care providers remain critical to screen and treat this condition.

摘要

卡立普多(即索马、索普罗多、瓦纳多姆)是一种用于缓解肌肉疼痛症状的肌肉松弛剂。过去通过病例报告已充分证实卡立普多在成年人中的成瘾可能性。自2007年以来,“未来监测”研究报告了青少年滥用卡立普多的情况,但迄今为止尚未发表任何病例研究或相关研究。由于其半衰期相对较短,耐受性和依赖性发展相当迅速,会导致负面的心理健康结果。医疗保健提供者的认识和教育对于筛查和治疗这种情况仍然至关重要。