Health Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Departments of Gynecology and Obstetrics, State University of Campinas, Campinas, Brazil.
Int J Gynaecol Obstet. 2021 May;153(2):200-219. doi: 10.1002/ijgo.13561. Epub 2021 Feb 22.
Genitourinary syndrome of menopause (GSM) negatively affects sexual function and quality of life. Techniques like laser and radiofrequency are being used to manage GSM, particularly in women with contraindications for hormone therapy.
To verify whether the physical methods of laser and radiofrequency can be recommended as safe and effective options for the treatment of GSM/urinary urgency or incontinence in pre- and postmenopausal women.
Databases were comprehensively searched using combinations of the following keywords in any language: "postmenopause"; "genitourinary syndrome of menopause"; "vaginal atrophy"; "radiofrequency"; and "laser."
Full articles of case-control, cross-sectional, cohort, randomized clinical trials, and quasi-randomized or controlled clinical trials were included.
All authors independently evaluated the design of the studies for quality of reporting, risk of bias, and quality of evidence.
Of the included 49 studies, 37 were on the CO laser, 10 on the Erbium laser, and two on radiofrequency.
Laser and radiofrequency therapy could be promising and safe therapeutic options for GSM/urinary incontinence. However, the study findings cannot be generalized until new randomized clinical trials are performed that confirm the strength of the evidence. This review has been registered with PROSPERO: CRD42020141913.
绝经后泌尿生殖系统综合征（GSM）会对性功能和生活质量产生负面影响。激光和射频等技术被用于治疗 GSM，特别是对于激素治疗禁忌的女性。
验证激光和射频等物理方法是否可以作为治疗绝经前和绝经后女性 GSM/尿急或尿失禁的安全有效选择。
使用任何语言的以下关键词组合对数据库进行全面检索：“绝经后”；“绝经后泌尿生殖系统综合征”；“阴道萎缩”；“射频”和“激光”。
纳入了病例对照、横断面、队列、随机临床试验以及准随机或对照临床试验的全文。
所有作者均独立评估研究设计的报告质量、偏倚风险和证据质量。
纳入的 49 项研究中，37 项为 CO 激光，10 项为铒激光，2 项为射频。
激光和射频治疗可能是 GSM/尿失禁有前途且安全的治疗选择。然而，在进行新的随机临床试验证实证据强度之前，研究结果不能推广。本综述已在 PROSPERO 上注册：CRD42020141913。
