Department of Dentistry, Faculty of Medicine in Hradec Králové, Charles University, and University Hospital in Hradec Králové, Czech Republic.
Department of Dentistry, Faculty of Medicine, Charles University and University Hospital in Pilsen, Czech Republic.
Acta Medica (Hradec Kralove). 2020;63(4):145-149. doi: 10.14712/18059694.2020.56.
Recurrent aphthous stomatitis (RAS) is the most common chronic oral mucosal lesion affecting up to 25% of the population. The diagnosis is based on well-defined clinical characteristics, but the precise aetiology and pathogenesis remain unclear. The treatment of RAS should be based on the identification and control of possible predisposing factors. A wide range of topical medicaments is available as antiseptics, anti-inflammatory drugs and corticosteroids. The systemic treatment is indicated in patients with continuous and aggressive manifestation, which is extremely rare in children. The present article provides a review of the current concept and knowledge of the aetiology, pathogenesis, and management of RAS in the paediatric population.
复发性阿弗他口炎（RAS）是最常见的慢性口腔黏膜病变，影响多达 25%的人群。该诊断基于明确的临床特征，但确切的病因和发病机制仍不清楚。RAS 的治疗应基于识别和控制可能的诱发因素。有广泛的局部药物可供选择，如防腐剂、抗炎药和皮质类固醇。全身治疗适用于具有持续性和侵袭性表现的患者，这种情况在儿童中极为罕见。本文综述了儿科人群 RAS 的病因、发病机制和治疗的最新概念和知识。
