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心脏肿块:病理和手术特征——一项多中心研究。

Cardiac Masses: Pathological and Surgical Features - A Multicenter Study.

机构信息

Pathology Training Clinic, Kayseri City Hospital, Kayseri, Turkey.

Department of Cardiovascular Surgery, Faculty of Medicine, Erciyes University, Kayseri, Turkey.

出版信息

Braz J Cardiovasc Surg. 2021 Oct 17;36(5):656-662. doi: 10.21470/1678-9741-2020-0225.

Abstract

INTRODUCTION

This study aimed to review the surgical excision results and pathological diagnostic features of rarely observed intracardiac masses in the light of the literature. Diagnosis and treatment approaches and complications were evaluated.

METHODS

Forty patients (26 females, mean age 52.1±18.1 years, and 14 males, mean age 48.1±20.5 years), who had undergone surgery for intracardiac mass between January 2008 and December 2018, were included in this study. The patients' data were analyzed retrospectively from the medical records of both centers.

RESULTS

When the pathological diagnoses were examined, 85.8% of the masses (n=35) were observed to be benign (benign tumor + hydatid cyst) and 14.2% (n=5) were malignant tumors. The masses were most commonly located in the left atrium (75%, n=30), and this was followed by the right ventricle (12.5%, n=5), right atrium (7.5%, n=3), and left ventricle (5%, n=2). Of the patients, 7.5% (n=3) died during the early postoperative period, while the remaining 92.5% (n=37) were discharged with healing. In the histopathological diagnosis of the patients, in whom in-hospital major adverse cardiovascular events were observed, there was malignancy in two cases.

CONCLUSION

Intracardiac masses, which have pathological features, are severe life-threatening problems. In-hospital mortality is frequent, especially in malignant tumors.

摘要

引言

本研究旨在结合文献回顾罕见的心脏内肿块的手术切除结果和病理诊断特征。评估了诊断和治疗方法及并发症。

方法

本研究纳入了 2008 年 1 月至 2018 年 12 月期间在两个中心因心脏内肿块接受手术的 40 名患者(26 名女性,平均年龄 52.1±18.1 岁,14 名男性,平均年龄 48.1±20.5 岁)。回顾性分析了这些患者的病历资料。

结果

检查病理诊断时,85.8%(n=35)的肿块为良性(良性肿瘤+包虫囊肿),14.2%(n=5)为恶性肿瘤。肿块最常见于左心房(75%,n=30),其次是右心室(12.5%,n=5)、右心房(7.5%,n=3)和左心室(5%,n=2)。7.5%(n=3)的患者在术后早期死亡,而其余 92.5%(n=37)治愈出院。在观察到院内主要不良心血管事件的患者的组织病理学诊断中,有 2 例为恶性肿瘤。

结论

具有病理特征的心脏内肿块是严重的危及生命的问题。院内死亡率较高,尤其是恶性肿瘤。

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