Okoh D S, Akinshipo A O, Butali A, Omitola O G, Sigbeku O F, Soyele O O, Osunde O D, Taiwo A O, Ibikunle A A, Omeje K U, Lawal A O, Fomete B, Adeola H A
Department of Dental and Maxillofacial Surgery, Oral and Maxillofacial Pathology and Medicine Unit, Federal Medical Centre, Asaba, Delta State, Nigeria.
Department of Oral and Maxillofacial Pathology and Biology, College of Medicine, University of Lagos, Lagos, Nigeria.
Niger J Clin Pract. 2020 Dec;23(12):1695-1701. doi: 10.4103/njcp.njcp_315_20.
Many studies have investigated the burden of odontogenic tumor (OT) in Nigeria; however, the true burden and prevalence of these lesions are not known because these studies are based on a center/region.
Hence, the aim of this study is to evaluate the true burden of OTs in Nigeria, using a multicenter approach.
This is a 10-year retrospective cross-sectional study of OT seen in eight tertiary health institutions in different geographic locations in Nigeria.
A total of 990 cases were included in this study. The highest prevalence of OT was in the third decade of life (n = 274, 27.7%). Most lesions were benign (n = 961, 97.1%), with a slight male preponderance; and the mandible was the commonest site (n = 814, 82.2%). There were a significant association between the diagnosed OTs and the age group and site (P = 0.002 and 0.031, respectively).
OTs showed a slightly higher preponderance in males, occurring mostly in the third decade. Benign lesions were frequent and ameloblastoma was the commonest OT. Variations exist in the occurrence of OTs from the different geographic locations in Nigeria. This study essentially sheds a broader light on the clinicopathological distribution of OTs across Nigeria, using a large multicenter approach.
许多研究调查了尼日利亚牙源性肿瘤（OT）的负担；然而，由于这些研究是基于一个中心/地区，这些病变的真实负担和患病率尚不清楚。
因此，本研究的目的是采用多中心方法评估尼日利亚OT的真实负担。
这是一项对尼日利亚不同地理位置的八家三级医疗机构中所见OT进行的为期10年的回顾性横断面研究。
本研究共纳入990例病例。OT的最高患病率出现在生命的第三个十年（n = 274，27.7%）。大多数病变为良性（n = 961，97.1%），男性略占优势；下颌骨是最常见的部位（n = 814，82.2%）。诊断出的OT与年龄组和部位之间存在显著关联（P分别为0.002和0.031）。
OT在男性中略占优势，大多发生在第三个十年。良性病变很常见，成釉细胞瘤是最常见的OT。尼日利亚不同地理位置的OT发生率存在差异。本研究通过大型多中心方法，从本质上更广泛地揭示了OT在尼日利亚的临床病理分布情况。
