Adebayo Ezekiel Taiwo, Ajike Sunday Olusegun, Adekeye Emmanuel Oladepo
Maxillofacial Unit, Department of Dental Surgery, Ahmadu Bello University Teaching Hospital, Kaduna, Nigeria.
J Oral Maxillofac Surg. 2005 Jun;63(6):811-9. doi: 10.1016/j.joms.2004.03.022.
To analyze 318 odontogenic tumors seen at a tertiary oral care center in Kaduna, Nigeria for comparison with findings in previous Nigerian and world records.
A retrospective survey of odontogenic tumors based on the classification of Kramer et al was undertaken at the Maxillofacial Unit, Ahmadu Bello University Teaching Hospital, Kaduna, Nigeria, from all histopathologically proven cases of tumors and tumor-like lesions of the oral and perioral structures. Data were retrieved from case notes, radiographs, histopathology results, and follow-up records. Information collected were used to complete a questionnaire and subjected to analysis.
There were 990 tumor and tumor-like lesions of the oral and perioral structures, of which 318 were odontogenic tumors (32%). Twelve histopathologic types of odontogenic tumors were found with more benign (n=314; 99%) than malignant (n=4; 1%). Ameloblastoma made up 233 (73%) of the tumors, followed by odontogenic myxoma (n=38; 12%), ameloblastic fibroma (n=9; 3%), and the adenomatoid odontogenic tumor (2%). Three cases of calcifying odontogenic cyst were co-existent with ameloblastoma (2) and ameloblastic fibro-odontoma (1). Among 275 surgically treated odontogenic tumors, enucleation was performed in 64 cases (23%), dentoalveolar segment resection with preservation of lower border of the mandible (n=33; 12%), segmental resection (n=168; 61%), and composite resection (n=9; 3%); 1 case was deemed inoperable. At least 8 cases of ameloblastoma (13%) recurred out of 60 followed up.
Ameloblastoma is a fairly common tumor of Nigerian Africans accounting for 73% of odontogenic tumors and 24% of all tumors and tumor-like lesions of the oral and perioral structures. Various forms of resection are practiced to eradicate the tumor in view of the late presentation in our environment. Patients in Nigeria do not often return for follow-up reviews. A minimum of 5 years of follow-up reviews are necessary after treatment of ameloblastoma.
分析在尼日利亚卡杜纳一家三级口腔护理中心所见的318例牙源性肿瘤，以便与先前尼日利亚及世界记录中的结果进行比较。
在尼日利亚卡杜纳阿哈穆杜·贝洛大学教学医院颌面科，基于克莱默等人的分类对牙源性肿瘤进行回顾性调查，纳入所有经组织病理学证实的口腔及口周结构肿瘤和肿瘤样病变病例。数据从病例记录、X光片、组织病理学结果及随访记录中获取。收集的信息用于填写问卷并进行分析。
口腔及口周结构有990例肿瘤和肿瘤样病变，其中318例为牙源性肿瘤（32%）。发现了12种组织病理学类型的牙源性肿瘤，良性肿瘤更多（n = 314；99%），恶性肿瘤较少（n = 4；1%）。成釉细胞瘤占肿瘤的233例（73%），其次是牙源性黏液瘤（n = 38；12%）、成釉细胞纤维瘤（n = 9；3%）和腺样牙源性肿瘤（2%）。3例钙化牙源性囊肿分别与成釉细胞瘤（2例）和成釉细胞纤维牙瘤（1例）并存。在275例接受手术治疗的牙源性肿瘤中，64例（23%）进行了摘除术，33例（12%）进行了保留下颌骨下缘的牙槽骨段切除术，168例（61%）进行了节段性切除术，9例（3%）进行了联合切除术；1例被认为无法手术。在60例接受随访的病例中，至少8例（13%）成釉细胞瘤复发。
成釉细胞瘤是尼日利亚非洲人相当常见的肿瘤，占牙源性肿瘤的73%，占口腔及口周结构所有肿瘤和肿瘤样病变的24%。鉴于我们地区患者就诊较晚，采用了多种切除方式来根除肿瘤。尼日利亚患者通常不常回来进行随访复查。成釉细胞瘤治疗后至少需要5年的随访复查。
