Sundar Kaushik, Paulraj Sabharisundarvel, Choudhury Shuvro Roy, Hassan Haseeb, Sengupta Judhajit, Pattari Sanjib Kumar
Rabindranath Tagore International Institute of Cardiac Sciences, Kolkata, India.
Neurointervention. 2021 Mar;16(1):83-87. doi: 10.5469/neuroint.2020.00304. Epub 2020 Dec 28.
Cerebral venous thrombosis (CVT) is a rare clinical entity, with clinical presentations extending from headache and seizures to coma and death. For adults developing progressive neurological worsening despite adequate medical management, endovascular thrombolysis and/or mechanical thrombectomy may be considered as treatment options. We present one such patient with CVT who developed seizures and slipped into a coma, despite best medical management. A large-bore aspiration catheter was used as a standalone system for the endovascular procedure. The venous sinuses were successfully re-canalized. The patient was discharged a week later with a modified Rankin scale of 2. Studies show that endovascular thrombolysis used alone or in conjunction with thrombectomy for CVT has a higher risk of hemorrhagic complications. If we were to use mechanical thrombectomy devices (that are specifically designed for intracranial clot retrieval) as a stand-alone system, we would probably have better clinical outcomes with a lower risk of hemorrhagic complications.
脑静脉血栓形成(CVT)是一种罕见的临床病症,临床表现从头痛、癫痫发作到昏迷和死亡不等。对于尽管接受了充分的药物治疗仍出现进行性神经功能恶化的成年人,血管内溶栓和/或机械取栓术可被视为治疗选择。我们报告了一名患有CVT的患者,尽管接受了最佳的药物治疗,但仍出现癫痫发作并陷入昏迷。一根大口径抽吸导管被用作血管内手术的独立系统。静脉窦成功再通。患者一周后出院,改良Rankin量表评分为2分。研究表明,单独使用血管内溶栓或与取栓术联合用于CVT时,出血并发症的风险更高。如果我们将机械取栓装置(专门设计用于颅内血栓取出)作为独立系统使用,可能会获得更好的临床结果,且出血并发症风险更低。