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使用大口径抽吸导管和支架取栓器进行血管内机械取栓治疗妊娠合并脑静脉窦血栓形成:一例报告

Endovascular Mechanical Thrombectomy with a Large-Bore Aspiration Catheter and Stent Retriever for Cerebral Venous Sinus Thrombosis in Pregnancy: A Case Report.

作者信息

Shimizu Tsuyoshi, Sakamoto Makoto, Amisaki Hidefumi, Kuwamoto Yuhei, Nakajima Sadao, Torihashi Koichi, Uno Tetsuji, Kambe Atsushi, Kurosaki Masamichi

机构信息

Division of Neurosurgery, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Tottori, Japan.

Department of Neurosurgery, Sanin Rosai Hospital, Yonago, Tottori, Japan.

出版信息

J Neuroendovasc Ther. 2022;16(8):413-418. doi: 10.5797/jnet.cr.2021-0092. Epub 2022 Jan 29.

Abstract

OBJECTIVE

A case of cerebral venous sinus thrombosis (CVST) during pregnancy effectively recanalized by endovascular mechanical thrombectomy with the combined use of an aspiration catheter and a stent retriever is reported.

CASE PRESENTATION

A 27-year-old woman at eight weeks' gestation developed sudden onset of right hemiparalysis and seizures and was referred to our hospital. Her National Institutes of Health Stroke Scale score on admission was 23. On MRI, diffusion-weighted imaging showed a hyperintensity area in the left frontal lobe, and T2* imaging showed hemorrhagic infarction in the same area. MR venography showed obstruction of the anterior two-thirds of the superior sagittal sinus (SSS). Anticoagulant therapy with heparin was started, but since the venous return was expected to be severely impaired, mechanical thrombectomy by endovascular surgery was selected, hoping to resolve symptoms early. Using a large-bore aspiration catheter in combination with a stent retriever, it was possible to safely guide the aspiration catheter into the anterior half of the SSS. The use of a large-bore aspiration catheter enabled retrieval of a large amount of thrombus in a short time, and complete recanalization was achieved. The patient's hemiplegia and aphasia improved significantly within a week after the procedure, and she was discharged without sequelae.

CONCLUSION

Mechanical endovascular therapy of CVST performed with a combination of a large-bore aspiration catheter and a stent retriever should be considered particularly for patients with severe neurological symptoms or intracranial hemorrhage and for those who do not respond to anticoagulation therapy.

摘要

目的

报告1例妊娠期脑静脉窦血栓形成(CVST)患者,通过血管内机械取栓术,联合使用抽吸导管和支架取栓器,实现了有效的再通。

病例介绍

一名27岁妊娠8周的女性突然出现右半身麻痹和癫痫发作,被转诊至我院。入院时她的美国国立卫生研究院卒中量表评分为23分。MRI检查显示,弥散加权成像在左侧额叶有一个高信号区,T2*成像显示同一区域有出血性梗死。磁共振静脉血管造影显示上矢状窦(SSS)前三分之二阻塞。开始使用肝素进行抗凝治疗,但由于预计静脉回流会严重受损,因此选择了血管内手术进行机械取栓,希望能尽早缓解症状。联合使用大口径抽吸导管和支架取栓器,能够安全地将抽吸导管引导至上矢状窦的前半部分。使用大口径抽吸导管可在短时间内取出大量血栓,并实现了完全再通。术后一周内,患者的偏瘫和失语症状明显改善,出院时无后遗症。

结论

对于有严重神经症状或颅内出血的患者以及对抗凝治疗无反应的患者,尤其应考虑采用大口径抽吸导管和支架取栓器联合进行CVST的机械血管内治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d13/10370632/e0a5fb9b56a2/jnet-16-413-g001.jpg

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