Department of Cardiology, Dokuz Eylul University School of Medicine, Izmir, Turkey.
Department of Cardiology, Faculty of Medicine, Goztepe Medicalpark Hospital, Bahcesehir University, Istanbul, Turkey.
J Cardiovasc Electrophysiol. 2021 Feb;32(2):360-369. doi: 10.1111/jce.14852. Epub 2021 Jan 9.
Mahaim-type accessory pathways (MAPs) are generally right-sided due to the embryological differentiation, but left-sided localization is also possible. This study aims to compare the clinical and electrophysiological characteristics of right- and left-sided MAPs.
Of 251 patients diagnosed with AP by electrophysiological study between November 2015 and February 2020, 12 patients with MAP were included (right sided n = 8, left sided n = 4). MAP was diagnosed if; (1) no retrograde conduction; (2) anterograde decremental conduction; (3) adenosine sensitivity; and (4) Mahaim potential at successful ablation site were present.
Ten of twelve MAPs were clustered on the lateral walls of the mitral (n = 3, 75%) and tricuspid annuli (n = 7, 87.5%). Right-sided MAPs were mostly long pathways extending toward the conduction system whereas left-sided MAPs were short extending toward the neighboring myocardium. For right- and left-sided APs, the median QRS times were 129 and 156 ms (p = .042), the median V -RV intervals were -12 and 64 ms (p = .007), the median QRS-V intervals were 16 and 86 ms (p = .120), and the median V -QRS interval was -8 and 12 ms (p = .017), respectively. Coexistence of dual atrioventricular node physiology was observed only in right-sided APs (n = 3, 37.5%).
MAPs are more typically located on the right but may rarely be seen on the left. Catheter ablation was associated with high success without complications.
Mahaim 型附加径路(MAP)通常由于胚胎分化而位于右侧,但也可能位于左侧。本研究旨在比较右侧和左侧 MAP 的临床和电生理特征。
在 2015 年 11 月至 2020 年 2 月期间通过电生理研究诊断为 AP 的 251 例患者中,纳入了 12 例 MAP 患者(右侧 n=8,左侧 n=4)。如果存在以下情况,则诊断为 MAP:(1)无逆行传导;(2)顺行递减传导;(3)腺苷敏感性;(4)在成功消融部位存在 Mahaim 电位。
12 例 MAP 中有 10 例聚集在二尖瓣(n=3,75%)和三尖瓣环的侧壁(n=7,87.5%)。右侧 MAP 主要是向传导系统延伸的长径路,而左侧 MAP 是向邻近心肌延伸的短径路。对于右侧和左侧的 AP,QRS 时间的中位数分别为 129ms 和 156ms(p=0.042),V-RV 间期的中位数分别为-12ms 和 64ms(p=0.007),QRS-V 间期的中位数分别为 16ms 和 86ms(p=0.120),V-QRS 间期的中位数分别为-8ms 和 12ms(p=0.017)。仅在右侧 AP 中观察到双重房室结生理共存(n=3,37.5%)。
MAP 更常见于右侧,但也可能罕见地见于左侧。导管消融术成功率高,且无并发症。