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比较慢性药物过度使用性头痛中枕大神经与枕大神经+眶上神经阻滞的效果。

Comparison of greater occipital nerve and greater occipital nerve + supraorbital nerve block effect in chronic medication overuse headache.

出版信息

Turk J Med Sci. 2021 Jun 28;51(3):1065-1070. doi: 10.3906/sag-2009-101.

DOI:10.3906/sag-2009-101
PMID:33356027
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8283500/
Abstract

BACKGROUND /AIM: In this study, we aimed to compare the efficacy of greater occipital nerve (GON) block alone and GON combined with supraorbital nerve (SON) block in the treatment of medication overuse headache (MOH).

MATERIAL AND METHODS

82 patients were divided into two groups: 41 patients were administered bilateral GON block while the other 41 patients GON + SON block. Nerve blocks were administered every 10 days for a total of 5 sessions. After each administration and 20 days after the last injection, information on pre and post treatment numerical rating scale (NRS) score, number of painful days, analgesic intake, duration of pain were collected.

RESULTS

The decrease in headache evaluation parameters was similar in both groups after the block. The NRS scores in the GON and GON + SON groups before the treatment was (8.2 ± 0.7, 8.5 ± 0.7), the number of painful days in a month was (21.4 ± 6.9, 21.2 ± 4.6 days), the number of analgesics taken monthly was (45 ± 25.6, 47.5 ± 29.9), the duration of pain was (44.9 ± 24.6, 41.7 ± 22.8 h), respectively. On the 60th day of treatment, the NRS scores in the GON and GON + SON groups were found to be (6.8 ± 2.5, 4.8 ± 2.3), the number of painful days in a month was (4.2 ± 3.3, 2.2 ± 1.5), respectively. The number of monthly analgesic consumption was (4.4 ± 3.8, 0.9 ± 1.2), and the duration of pain was (28.4 ± 19.3, 19.4 ± 16.1 h).

CONCLUSION

This study showed significant reductions in headache parameters in both groups. However, NRS score, analgesic intake, number of painful days, and pain duration significantly better improved in the GON block added SON block group.

摘要

背景/目的:本研究旨在比较单纯使用枕大神经(GON)阻滞与 GON 联合眶上神经(SON)阻滞治疗药物过度使用性头痛(MOH)的疗效。

材料和方法

82 例患者分为两组:41 例患者接受双侧 GON 阻滞,另 41 例患者接受 GON+SON 阻滞。神经阻滞每 10 天给药 1 次,共 5 次。每次给药后和最后一次注射后 20 天,收集治疗前后数字评分量表(NRS)评分、疼痛天数、镇痛药摄入、疼痛持续时间的信息。

结果

阻滞治疗后两组头痛评估参数的下降相似。GON 组和 GON+SON 组治疗前 NRS 评分分别为(8.2±0.7、8.5±0.7),每月疼痛天数分别为(21.4±6.9、21.2±4.6 天),每月镇痛药用量分别为(45±25.6、47.5±29.9),疼痛持续时间分别为(44.9±24.6、41.7±22.8 h)。治疗第 60 天,GON 组和 GON+SON 组 NRS 评分分别为(6.8±2.5、4.8±2.3),每月疼痛天数分别为(4.2±3.3、2.2±1.5),每月镇痛药用量分别为(4.4±3.8、0.9±1.2),疼痛持续时间分别为(28.4±19.3、19.4±16.1 h)。

结论

本研究显示两组头痛参数均显著降低。然而,GON 阻滞联合 SON 阻滞组的 NRS 评分、镇痛药摄入、疼痛天数和疼痛持续时间明显改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc94/8283500/3b4b7f28a845/turkjmedsci-51-1065-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc94/8283500/a2da15d7b298/turkjmedsci-51-1065-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc94/8283500/a1dac9a20e05/turkjmedsci-51-1065-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc94/8283500/321166a9d783/turkjmedsci-51-1065-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc94/8283500/3b4b7f28a845/turkjmedsci-51-1065-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc94/8283500/a2da15d7b298/turkjmedsci-51-1065-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc94/8283500/a1dac9a20e05/turkjmedsci-51-1065-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc94/8283500/321166a9d783/turkjmedsci-51-1065-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc94/8283500/3b4b7f28a845/turkjmedsci-51-1065-fig004.jpg

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