以家庭为中心的心理支持有助于改善晚期前列腺癌患者的疾病认知和生活质量。

[Family-centered psychological support helps improve illness cognition and quality of life in patients with advanced prostate cancer].

作者信息

Han Jing, Yang Dong-Liang, Liu Ji-Hai, Li Bing-Heng, Kan Yi, Ma Sai, Mao Li-Jun

机构信息

School of Nursing, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.

Department of Urology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221000, China.

出版信息

Zhonghua Nan Ke Xue. 2020 Jun;26(6):505-512.

PMID:33356038

Abstract

OBJECTIVE

To explore the effect of family-centered psychological support (FCPS) on illness cognition and quality of life in patients with advanced prostate cancer (PCa).

METHODS

Using a randomized controlled study design, we divided 84 advanced PCa patients into an intervention group and a control group, all provided with PCa-related knowledge and answers to their questions, while the former group with FCPS in addition. Before, immediately after and at 1 and 3 months after intervention, we evaluated the effectiveness using the Illness Cognition Questionnaire (ICQ) and Functional Assessment of Cancer Therapy － Prostate (FACT-P).

RESULTS

Totally, 78 of the patients completed the whole intervention procedure, 38 in the intervention and 40 in the control group. There were statistically significant differences between the intervention and control groups in the scores on the three factors of ICQ acceptance (17.89 ± 3.86 vs 15.20 ± 2.83, t = 3.528, P < 0.05), perceived benefits (18.68 ± 3.02 vs 17.08 ± 2.74, t = 2.465, P < 0.05) and helplessness (13.37 ± 3.00 vs 15.63 ± 3.11, t = －3.259, P < 0.05) immediately after intervention, and so were there at 1 and 3 months after intervention (P < 0.05). The patients in the intervention group showed remarkably higher quality of life scores than the controls immediately after (100.59 ± 11.66 vs 92.20 ± 9.54, t = 7.943, P < 0.05) and at 1 month (93.03 ± 13.33 vs83.55 ± 14.29, t = 3.481, P < 0.05) and 3 months after intervention (85.66 ± 17.39 vs 75.95 ± 16.66, t = 3.025, P < 0.05). The covariance analysis found that, excluding the time effect, FCPS significantly improved the positive illness cognition of the patients (P < 0.05).

CONCLUSIONS

Family-centered psychological support contributes to the positive illness cognition of the patients with advanced PCa and helps improve their quality of life, and therefore deserves to be popularized in clinical practice.

摘要

目的

探讨以家庭为中心的心理支持（FCPS）对晚期前列腺癌（PCa）患者疾病认知及生活质量的影响。

方法

采用随机对照研究设计，将84例晚期PCa患者分为干预组和对照组，两组均给予PCa相关知识及问题解答，干预组在此基础上给予FCPS。在干预前、干预后即刻、干预后1个月和3个月，使用疾病认知问卷（ICQ）和癌症治疗功能评估量表-前列腺（FACT-P）评估效果。

结果

共有78例患者完成了整个干预过程，其中干预组38例，对照组40例。干预组和对照组在干预后即刻ICQ接受度（17.89±3.86比15.20±2.83，t=3.528，P<0.05）、感知益处（18.68±3.02比17.08±2.74，t=2.465，P<0.05）和无助感（13.37±3.00比15.63±3.11，t=-3.259，P<0.05）这三个因子的得分上存在统计学显著差异，在干预后1个月和3个月时也是如此（P<0.05）。干预组患者在干预后即刻（100.59±11.66比92.20±9.54，t=7.943，P<0.05）、干预后1个月（93.03±13.33比83.55±14.29，t=3.481，P<0.05）和干预后3个月（85.66±17.39比75.95±16.66，t=3.025，P<0.05）的生活质量得分显著高于对照组。协方差分析发现，排除时间效应后，FCPS显著改善了患者的积极疾病认知（P<0.05）。