作为全眼炎急骤病程的病因因素。
as an aetiological factor of the fulminant course of panophthalmitis.
机构信息
Department of Maxillofacial Surgery, Heliodor Święcicki Clinical Hospital, University of Medical Sciences, Poznań, Poland.
Central Microbiology Laboratory, H. Swiecicki Clinical Hospital, University of Medical Sciences, Poznań, Poland.
出版信息
Ann Agric Environ Med. 2020 Dec 22;27(4):540-543. doi: 10.26444/aaem/122475. Epub 2020 Jun 5.
INTRODUCTION
The role of fungi in infections in immunocompromised patients is a growing problem in both diagnosis and treatment. Candida species are the most common cause of fungal, endogenous endophthalmitis and infections of the cornea.
CASE STUDY
A patient was admitted to hospital due to acute inflammation of the tissue of the left orbit, 1.5 years after the corneal penetrating transplantation of the left eye with intracapsular extraction of lens and simultaneous anterior vitrectomy. The microbiological system identified: Streptococcus pyogenes, Staphylococcus aureus, and Candida glabrata in the patient.
CONCLUSIONS
The factors conducive to fungal infections are: patient's old age, immune disorders and diabetes, as well as the presence of a necrotic tissue or a foreign body. All these parameters were met in this case. Only antibiotic therapy and long-term antifungal therapy, together with surgical debridement of the site of the ongoing infection produces clinical effects in such severe cases.
引言
在免疫功能低下患者的感染中，真菌的作用在诊断和治疗方面都是一个日益严重的问题。念珠菌属是真菌性、内源性眼内炎和角膜感染的最常见原因。
病例研究
一名患者因左眼经囊内晶状体摘出和同时行前段玻璃体切除术的穿透性角膜移植术后 1.5 年，左眼眶组织急性炎症而住院。微生物系统鉴定出患者有化脓性链球菌、金黄色葡萄球菌和光滑念珠菌。
结论
有利于真菌感染的因素有：患者年龄较大、免疫功能紊乱和糖尿病，以及存在坏死组织或异物。所有这些参数在本例中均存在。只有抗生素治疗和长期抗真菌治疗，以及对正在感染部位进行手术清创，才能在这种严重情况下产生临床效果。
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