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野生 中酚类物质的多样性:作为抗菌和抗氧化应用的宝贵资源。

Phenolics diversity among wild populations of : as a precious source for antimicrobial and antioxidant applications.

机构信息

Department of Horticultural Science, Faculty of Agriculture, Bu Ali Sina University, Hamedan, Iran.

Department of Agriculture, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G. C, Tehran, Iran.

出版信息

Nat Prod Res. 2022 Mar;36(5):1332-1336. doi: 10.1080/14786419.2020.1864369. Epub 2020 Dec 28.

Abstract

The genus L. belongs to the Lamiaceae family including several known species rich in natural compounds that are extensively used in pharmaceutical, food, and cosmetic industries. populations contain a broad diversity of flavonoids and phenolic acids. The present study aimed to explore biological and pharmacological effects including antimicrobial and antioxidant activities of nineteen populations () grown in Iran for the first time. High content of rosmarinic acid (RA) in (Gazan) (5.65 ± 0.33 mg/g DW) caused high antimicrobial activity against two bacteria (, ) and the fungus , while methanolic extract of (Taleghan) showed high antioxidant activity due to high content of salvianolic acid A (SAA) and quercetin (0.53 ± 0.04 and 0.49 ± 0.12 mg/g DW, respectively). Altogether these results can be considered for further commercial exploitations to meet the demands of the food and pharmaceutical industries.[Formula: see text].

摘要

属属于唇形科,包含多种富含天然化合物的已知物种,广泛应用于制药、食品和化妆品行业。 种群含有丰富的类黄酮和酚酸。本研究首次探索了伊朗 19 个 种群的生物和药理作用,包括抗菌和抗氧化活性。(Gazan)(5.65±0.33mg/g DW)中的迷迭香酸(RA)含量高,对两种细菌( 和 )和真菌 具有高抗菌活性,而来自 (Taleghan)的甲醇提取物由于含有较高的丹酚酸 A(SAA)和槲皮素(0.53±0.04 和 0.49±0.12mg/g DW),具有较高的抗氧化活性。总的来说,这些结果可以进一步商业开发利用,以满足食品和制药行业的需求。[公式: 见正文]。

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