SARS-CoV-2 经 COVID-19 感染孕妇的垂直传播：宫内传播综述。
Vertical Transmission of SARS-CoV-2 from COVID-19 Infected Pregnant Women: A Review on Intrauterine Transmission.
机构信息
Research, Development & Coordination Section, Pakistan Health Research Council, Islamabad, Pakistan.
出版信息
Fetal Pediatr Pathol. 2021 Feb;40(1):80-92. doi: 10.1080/15513815.2020.1865491. Epub 2020 Dec 27.
BACKGROUND
Fetal safety is a major concern with the global spread of COVID-19, but there is scarce information regarding vertical transmission and how it affects the fetus.
OBJECTIVE
To assess and summarize the currently available evidence on vertical transmission (probable/confirmed) of SARS-CoV-2 along with fetal outcomes.
METHODS
The current review was carried out from March to October 2020. Relevant databases were searched electronically. Pertinent articles were selected according to eligibility criteria and information was compiled.
RESULTS
In 16 selected articles there were total 498 COVID-19 infected pregnant women ranging in age between 15 and 45 years. Gestational age at the onset of COVID-19 symptoms ranged from 25-41 weeks. Vertical transmission (probable and confirmed) rate from series was 4.883% (23/471). Of 17 affected newborns (information available), 08 required NICU admission, 04 developed pneumonia and 04 required mechanical ventilation.
CONCLUSION
There is probable intrauterine transmission of SARS-CoV-2. Few adverse fetal outcomes are associated with COVID-19.
背景
随着 COVID-19 在全球范围内的传播，胎儿安全是一个主要关注点，但关于垂直传播及其对胎儿的影响的信息很少。
目的
评估和总结目前关于 SARS-CoV-2 垂直传播（可能/确诊）以及胎儿结局的可用证据。
方法
本次综述于 2020 年 3 月至 10 月进行。电子检索相关数据库。根据入选标准和信息汇总选择相关文章。
结果
在 16 篇选定的文章中，共有 498 名年龄在 15 至 45 岁之间的 COVID-19 感染孕妇。COVID-19 症状出现时的孕龄为 25-41 周。来自系列的垂直传播（可能和确诊）率为 4.883%（23/471）。在 17 名受影响的新生儿中（有信息可查），有 8 名需要入住新生儿重症监护病房，4 名患有肺炎，4 名需要机械通气。
结论
SARS-CoV-2 可能存在宫内传播。COVID-19 与一些不良胎儿结局相关。
Zotero 插件