Department of Cardiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Department of Cardiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Indian Heart J. 2020 Nov-Dec;72(6):563-569. doi: 10.1016/j.ihj.2020.09.009. Epub 2020 Sep 19.
Ventricular tachycardia (VT) is a major cause of morbidity in patients with cardiomyopathy. Radiofrequency ablation has emerged as the mainstay of the management of recurrent sustained VT in these patients. We describe the clinical characteristics, procedural and medium term outcomes of patients undergoing ablation of scar VT in a tertiary care center in India.
This was a single-center descriptive cohort study. All patients who underwent ablation for scar related VT were included. Endpoints were immediate procedural success, procedural complications and recurrence during follow up.
A total of 72 patients with scar VT underwent ablation with electroanatomic mapping. Previous myocardial infarction (MI) was the commonest etiology (69.4%) with arrhythmogenic right ventricular cardiomyopathy (ARVC) being the next common (19.4%). Acute procedural success was achieved in 69.4% patients, partial success in 9.7% and failure in 1 patient (1.4%). Outcome was labeled indeterminate in 19.4% who did not undergo post ablation VT induction. Procedural complications were seen in 4%. Follow up data was available in 95% of the patients with a mean follow up of 28.9 ± 22.8 months. At one year, freedom from VT was 83.8% and mortality was 13.2%. Overall mortality during follow up was 22.1% while VT recurrence was seen in 35.3%. Recurrence rate was higher in ARVC as compared to previous MI.
Ablation of scar VT has high acute success rates. Ablation is safe with low risk of major complications. Rates of recurrence are higher in patients with ARVC as compared to post MI VT.
室性心动过速(VT)是心肌病患者发病率的主要原因。射频消融术已成为这些患者复发性持续性 VT 治疗的主要手段。我们描述了在印度一家三级保健中心接受消融瘢痕性 VT 的患者的临床特征、手术过程和中期结果。
这是一项单中心描述性队列研究。所有因瘢痕相关 VT 而行消融术的患者均纳入研究。研究终点为即刻手术成功率、手术并发症和随访期间的复发率。
共有 72 例瘢痕性 VT 患者接受了电生理标测下的消融术。既往心肌梗死(MI)是最常见的病因(69.4%),致心律失常性右室心肌病(ARVC)是下一个常见病因(19.4%)。69.4%的患者获得了急性手术成功,9.7%的患者获得了部分成功,1 例(1.4%)患者手术失败。19.4%的患者因未行消融后 VT 诱发而无法明确手术结果。4%的患者出现手术并发症。95%的患者获得了随访数据,平均随访时间为 28.9±22.8 个月。1 年时,无 VT 发生率为 83.8%,死亡率为 13.2%。随访期间总死亡率为 22.1%,而 VT 复发率为 35.3%。与 MI 后 VT 相比,ARVC 患者的复发率更高。
瘢痕性 VT 的消融术具有较高的急性成功率。消融术安全,主要并发症风险低。与 MI 后 VT 相比,ARVC 患者的复发率更高。