Department of Radiology, University of Chicago, Chicago, IL 60637.
Department of Radiology, University of Chicago, Chicago, IL 60637.
J Vasc Interv Radiol. 2021 Mar;32(3):429-438. doi: 10.1016/j.jvir.2020.10.021. Epub 2020 Dec 24.
To evaluate the radiation dose differences for intraprocedural computed tomography (CT) imaging between cone-beam CT and angio-CT acquired during transarterial radioembolization (TARE) therapies for hepatocellular carcinoma.
A retrospective cohort of 22 patients who underwent 23 TARE procedures were selected. Patients were imaged in both cone-beam CT and angio-CT rooms as a part of their conventional treatment plan. Effective dose contributions from individual CT acquisitions as well as the cumulative dose contributions from procedural 3D imaging were evaluated. Angiography dose contributions were omitted. Cone-beam CT images were acquired on a C-arm Philips Allura system. Effective doses were evaluated by coupling previously published conversion factors (effective dose per dose-area product) to patient's dose-area product meter readings after the procedure. Angio-CT images were acquired on a hybrid Canon Infinix-i Aquilion PRIME system. Effective doses from angio-CT scans were estimated using Radimetrics. Comparisons of a single patient's dose differential between the 2 technologies were made.
The mean effective dose from a single CT scan was 6.42 mSv and 5.99 mSv in the cone-beam CT room and the angio-CT room, respectively (P = .3224), despite the greater field of view and average craniocaudal scan coverage in angio-CT. The mean effective dose summed across all CTs in a procedure was 12.89 mSv and 34.35 mSv in the cone-beam CT room and the angio-CT room, respectively (P = .0018).
The mean effective dose per CT scan is comparable between cone-beam CT and angio-CT when considered in direct comparison for a single patient.
评估肝细胞癌经动脉放射栓塞 (TARE) 治疗过程中锥形束 CT (CBCT) 和血管造影 CT 术中 CT 成像的辐射剂量差异。
选择了 22 例接受 23 次 TARE 治疗的患者进行回顾性队列研究。患者在 CBCT 和血管造影 CT 室进行成像，这是他们常规治疗计划的一部分。评估了单个 CT 采集的有效剂量贡献以及程序 3D 成像的累积剂量贡献。省略了血管造影剂量贡献。CBCT 图像在飞利浦 Allura C 臂系统上采集。在程序后，通过将先前发表的转换因子（剂量面积乘积的有效剂量）与患者的剂量面积乘积计量读数耦合，评估有效剂量。血管造影 CT 图像在佳能 Infinix-i Aquilion PRIME 混合系统上采集。使用 Radimetrics 估算血管造影 CT 扫描的有效剂量。对两种技术单个患者剂量差异进行了比较。
单次 CT 扫描的平均有效剂量分别为 6.42 mSv 和 5.99 mSv，在 CBCT 室和血管造影 CT 室，尽管血管造影 CT 的视野更大，平均颅尾扫描范围更广（P =.3224）。在程序中所有 CT 扫描的平均有效剂量分别为 12.89 mSv 和 34.35 mSv，在 CBCT 室和血管造影 CT 室（P =.0018）。
在对单个患者进行直接比较时，CBCT 和血管造影 CT 单次 CT 扫描的平均有效剂量相当。
