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杂交血管造影-CT 在经动脉放射性栓塞治疗中的应用:影像学研究。

Hybrid angiography-CT for transarterial radioembolization: a pictorial essay.

机构信息

Department of Radiology, Section of Vascular and Interventional Radiology, University of Chicago Medicine, 5841 S Maryland Ave, MC2026, Chicago, IL, USA.

出版信息

Abdom Radiol (NY). 2021 Jun;46(6):2850-2854. doi: 10.1007/s00261-020-02914-8. Epub 2021 Jan 4.

DOI:10.1007/s00261-020-02914-8
PMID:33394098
Abstract

Although hybrid angiography-CT (Angio-CT) has a long history of use for interventional oncology procedures, its applications for transarterial radioembolization (TARE) are not as well described in the literature. This pictorial essay demonstrates a single-institution experience with the utilization of an Angio-CT system for TARE treatment of hepatocellular carcinoma. Procedural images and clinical data for twenty-four patients who underwent initial angiographic mapping with hepatopulmonary shunt fraction assessment and or administration of Yttrium-90 (Y-90) microspheres using the Angio-CT system to date were reviewed. Cases were reviewed for examples that highlight the specific utility of Angio-CT. Three representative TARE cases were selected which illustrate unique advantages and applications of the Angio-CT system when performing TARE. These include the ability to optimally delineate hepatic vascular anatomy, accurately calculate liver volumes for dosimetry, and improve the detection and characterization of equivocal lesions. Angio-CT has unique advantages which can be applied to TARE treatment of patients with HCC. The technology has potential to be an especially effective tool for those who aim to be at the cutting edge of the rapidly growing field of interventional oncology.

摘要

虽然杂交血管造影-计算机断层扫描(Angio-CT)在介入肿瘤学治疗中已有很长的应用历史,但在文献中对其在经动脉放射性栓塞(TARE)中的应用描述并不多。本影像学专题论文展示了单机构使用 Angio-CT 系统治疗肝细胞癌的经验。迄今为止,对 24 名接受初始血管造影映射的患者的程序图像和临床数据进行了回顾,这些患者接受了肝肺分流分数评估,并使用 Angio-CT 系统进行钇-90(Y-90)微球的给药。对病例进行了回顾,以举例说明 Angio-CT 的具体用途。选择了三个有代表性的 TARE 病例,这些病例说明了在进行 TARE 时 Angio-CT 系统的独特优势和应用。这些优势包括能够最佳地描绘肝血管解剖结构,准确计算肝脏体积进行剂量学计算,以及提高对可疑病变的检测和定性。Angio-CT 在治疗 HCC 患者的 TARE 中具有独特的优势。该技术对于那些希望处于介入肿瘤学快速发展领域前沿的人来说,具有成为一种特别有效的工具的潜力。

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本文引用的文献

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Transarterial radioembolization using yttrium-90 microspheres in the treatment of hepatocellular carcinoma: a review on clinical utility and developments.经动脉放射性栓塞术用钇-90 微球治疗肝细胞癌:临床应用和进展综述。
J Hepatocell Carcinoma. 2014 Nov 3;1:163-82. doi: 10.2147/JHC.S50472. eCollection 2014.
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Br J Radiol. 2024 Feb 2;97(1154):353-362. doi: 10.1093/bjr/tqad056.
4
Efficacy of Yttrium-90 Transarterial Radioembolisation in Advanced Hepatocellular Carcinoma: An Experience With Hybrid Angio-Computed Tomography and Glass Microspheres.钇-90经动脉放射性栓塞治疗晚期肝细胞癌的疗效:混合血管造影-计算机断层扫描及玻璃微球的应用经验
J Clin Exp Hepatol. 2024 May-Jun;14(3):101342. doi: 10.1016/j.jceh.2023.101342. Epub 2023 Dec 26.
5
Liver Tumor Enhancement at Hybrid Angio-CT and Comparison With Tumor and Hepatic Parenchymal Distribution of Yttrium-90 Microspheres by Positron Emission Tomography.混合血管造影CT下肝脏肿瘤增强及与正电子发射断层扫描钇-90微球在肿瘤和肝实质分布的比较
Cureus. 2023 Dec 3;15(12):e49861. doi: 10.7759/cureus.49861. eCollection 2023 Dec.
6
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