Bioscience Institute, University of Passo Fundo (UPF), Passo Fundo, RS, Brazil; The International Zebrafish Neuroscience Research Consortium (ZNRC), Slidell, LA, USA; Moscow Institute of Physics and Technology, Moscow, Russia.
Bioscience Institute, University of Passo Fundo (UPF), Passo Fundo, RS, Brazil; Postgraduate Program in Environmental Sciences, University of Passo Fundo (UPF), Passo Fundo, Brazil.
Neurosci Biobehav Rev. 2021 May;124:1-15. doi: 10.1016/j.neubiorev.2020.12.014. Epub 2020 Dec 20.
Color is an important environmental factor that in multiple ways affects human and animal behavior and physiology. Widely used in neuroscience research, various experimental (animal) models may help improve our understanding of how different colors impact brain and behavioral processes. Complementing laboratory rodents, the zebrafish (Danio rerio) is rapidly emerging as an important novel model species to explore complex neurobehavioral processes. The growing utility of zebrafish in biomedicine makes it timely to consider the role of colors in their behavioral and physiological responses. Here, we summarize mounting evidence implicating colors as a critical variable in zebrafish models and neurobehavioral traits, with a particular relevance to CNS disease modeling, genetic and pharmacological modulation, as well as environmental enrichment and animal welfare. We also discuss the growing value of zebrafish models to study color neurobiology and color-related neurobehavioral phenomics, and outline future directions of research in this field.
颜色是一个重要的环境因素，它以多种方式影响着人类和动物的行为和生理。颜色在神经科学研究中被广泛应用，各种实验（动物）模型可以帮助我们更好地理解不同颜色如何影响大脑和行为过程。斑马鱼（Danio rerio）作为一种新兴的重要新型模式生物，正在迅速崛起，可用于探索复杂的神经行为过程。斑马鱼在生物医学中的应用日益广泛，因此及时考虑颜色在其行为和生理反应中的作用非常重要。在这里，我们总结了越来越多的证据，表明颜色是斑马鱼模型和神经行为特征的一个关键变量，特别是与中枢神经系统疾病建模、遗传和药理学调节以及环境丰富和动物福利有关。我们还讨论了斑马鱼模型在研究颜色神经生物学和与颜色相关的神经行为表型方面的日益重要性，并概述了该领域未来的研究方向。
