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阴道上皮样恶性外周神经鞘瘤险些被误诊为晚期宫颈癌：一例报告

Vaginal epithelioid malignant peripheral nerve sheath tumor nearly misdiagnosed as advanced cervical cancer: A case report.

作者信息

Guzin Kadir, Kinter Alp Koray, Bozdag Halenur, Kır Gozde, Sandal Kemal

机构信息

Department of Obstetrics and Gynecology, Kahramanmaraş Sütcü Imam University, Faculty of Medicine, Division of Gynecological Oncology, 46100, Onikişubat, Kahramanmaraş, Turkey.

Department of Obstetrics and Gynecology, Istanbul Medeniyet University Göztepe Education and Research Hospital, Doktor Erkin Caddesi Kadıköy, İstanbul, Turkey.

出版信息

Int J Surg Case Rep. 2021 Jan;78:241-246. doi: 10.1016/j.ijscr.2020.12.046. Epub 2020 Dec 18.

DOI:10.1016/j.ijscr.2020.12.046
PMID:33360976
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7772358/
Abstract

A 56-year-old woman was referred to our hospital with a pathological diagnosis of squamous cell carcinoma of the cervix. We performed a re-biopsy of the vaginal mass and cervical conization. The mass was originally reported as an epithelioid MPNST after re-biopsy. Strong diffuse S-100 positivity, epithelioid morphology of the lesion, and negativity to all other immune histochemical markers confirmed the diagnosis of epithelioid MPNST. Cervical conization specimen was negative for any neoplasms.

摘要

一名56岁女性因宫颈鳞状细胞癌病理诊断被转诊至我院。我们对阴道肿物进行了再次活检及宫颈锥切术。再次活检后肿物最初报告为上皮样恶性外周神经鞘膜瘤。弥漫性强S-100阳性、病变的上皮样形态以及对所有其他免疫组化标志物均为阴性，证实了上皮样恶性外周神经鞘膜瘤的诊断。宫颈锥切标本未发现任何肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61af/7772358/b350f75b1271/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61af/7772358/f460456b700a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61af/7772358/77b9694349f4/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61af/7772358/b350f75b1271/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61af/7772358/f460456b700a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61af/7772358/77b9694349f4/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61af/7772358/b350f75b1271/gr3.jpg

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Malignant Peripheral Nerve Sheath Tumor (MPNST) of the Uterine Cervix - A Systematic Literature Review and New Case Report with Possible New Therapeutic Approaches.子宫颈恶性周围神经鞘膜瘤——一项系统文献综述及具有可能新治疗方法的新病例报告
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