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口服避孕药联合使用与超重/肥胖的关系:对 2016 年埃塞俄比亚人口与健康调查的二次数据分析。

The association between combined oral contraceptive use and overweight/obesity: a secondary data analysis of the 2016 Ethiopia Demographic and Health Survey.

机构信息

Department of Public Health, College Of Health Science, Woldia University, Woldia, Ethiopia

Department of Public Health, College Of Health Science, Woldia University, Woldia, Ethiopia.

出版信息

BMJ Open. 2020 Dec 24;10(12):e039229. doi: 10.1136/bmjopen-2020-039229.

Abstract

OBJECTIVES

In this study, we aimed to assess the association between combined oral contraceptive (OC) use and overweight/obesity among Ethiopian adult women of reproductive age.

DESIGN, SETTING AND PARTICIPANTS: The data were extracted from the 2016 Ethiopia Demographic and Health Survey; these data were collected from nine regions and two city administrations. We analysed the data from a total of 11 018 women aged 18-49 years who met eligibility criteria.

MAIN OUTCOME MEASURES

We employed WHO criteria to classify the body mass index of women. Specifically we tested the association between combined OC utilisation with overweight/obesity after controlling for confounding variables.

RESULT

The prevalence of combined OC utilisation was 1.7% and the prevalence of overweight/obesity was 8.6% among adult women of reproductive age. Use of combined OC increases the odds of overweight/obesity by two times among adult women of reproductive age after controlling for potential confounders (adjusted OR=1.902 (1.064-3.399)).

CONCLUSION

In conclusion there is significant association between combined OC use and overweight/obesity. The findings have important implications for policymakers to design evidence based policy approachs to obesity prevention for women and at large for government to recognise the negative consequences of combined OC on women health.

摘要

目的

本研究旨在评估埃塞俄比亚育龄期成年女性口服避孕药(OC)的使用与超重/肥胖之间的关联。

设计、地点和参与者:数据来自 2016 年埃塞俄比亚人口与健康调查;这些数据来自九个地区和两个城市行政区。我们分析了符合入选标准的总共 11018 名年龄在 18-49 岁的女性的数据。

主要观察指标

我们采用世界卫生组织标准来对女性的体重指数进行分类。具体来说,我们在控制混杂因素后,测试了口服避孕药联合使用与超重/肥胖之间的关联。

结果

在育龄期成年女性中,口服避孕药联合使用的流行率为 1.7%,超重/肥胖的流行率为 8.6%。在控制潜在混杂因素后,口服避孕药联合使用使育龄期成年女性超重/肥胖的几率增加了两倍(调整后的 OR=1.902(1.064-3.399))。

结论

总之,口服避孕药联合使用与超重/肥胖之间存在显著关联。这些发现对政策制定者具有重要意义,他们可以制定基于证据的政策方法来预防女性肥胖,并且政府应该认识到口服避孕药联合使用对女性健康的负面影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39fd/7768964/c80e9b852e35/bmjopen-2020-039229f01.jpg

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