Department of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Clin Interv Aging. 2020 Dec 14;15:2363-2374. doi: 10.2147/CIA.S274262. eCollection 2020.
In recent years, behavioral activation (BA) has attracted increased interest as an effective depression treatment. However, empirical evidence supporting its effectiveness in non-Western countries is currently limited.
To examine the effectiveness of BA in reducing depressive symptoms, stress, and anxiety among Thai older adults with subthreshold depression.
A clustered randomized controlled trial was conducted in two health promoting hospitals (HPHs) in the Samut Songkhram province of Thailand. One hospital was used for the intervention (BA+usual care group) and the other for the control (usual care-only group). Each HPH randomly selected 41 eligible older adults residing in their jurisdictions to take part in the study. Mental health outcomes were assessed using the Thai Geriatric Depression Scale (TGDS) and Depression Anxiety Stress Scales (DASS). The BA effectiveness was evaluated using generalized estimating equations (GEE) at a group level and the reliable change index (RCI) at the individual level.
Over 9 months, the adjusted mean change in depression (TGDS) scores [-2.47 (95% CI: -3.84, -1.00)], mental health status (DASS), specifically depression and stress score [-1.47 and -1.87 (95% CI: -2.43, -0.50 and -2.94, -0.79, respectively)], improved significantly in the BA+usual care group compared to the usual care-only group, whereas anxiety score improved significantly only at 6 months [-0.87 (95% CI: -1.52, -0.23)]. Additional RCI analysis showed that BA was directly associated with 14.63 to 24.39% points increase in the reliable improvement of depressive outcome compared to the usual care-only group.
This study showed that the BA effectively improved depression, stress, and anxiety in older adults with subthreshold depression in a Thai community setting. Future research should evaluate the longer-term effectiveness of BA in diverse population groups.
近年来,行为激活(BA)作为一种有效的抑郁症治疗方法引起了越来越多的关注。然而,目前支持其在非西方国家有效性的实证证据有限。
检验行为激活(BA)在降低泰国有亚临床抑郁的老年人群的抑郁症状、压力和焦虑方面的有效性。
这是一项在泰国萨姆特松克拉姆省的两所健康促进医院(HPH)进行的集群随机对照试验。一所医院用于干预(BA+常规护理组),另一所用于对照(仅常规护理组)。每个 HPH 随机选择居住在其管辖范围内的 41 名符合条件的老年人参加研究。使用泰国老年抑郁量表(TGDS)和抑郁焦虑应激量表(DASS)评估心理健康结果。采用广义估计方程(GEE)在群体水平和可靠变化指数(RCI)在个体水平评估 BA 的有效性。
在 9 个月的时间里,BA+常规护理组的抑郁(TGDS)评分[调整后的平均变化值为-2.47(95%置信区间:-3.84,-1.00)]、心理健康状况(DASS),特别是抑郁和压力评分[-1.47 和-1.87(95%置信区间:-2.43,-0.50 和-2.94,-0.79,分别)]显著改善,而焦虑评分仅在 6 个月时显著改善[-0.87(95%置信区间:-1.52,-0.23)]。进一步的 RCI 分析表明,与仅常规护理组相比,BA 与抑郁结局可靠改善的 14.63%至 24.39%点的直接关联。
本研究表明,BA 可有效改善泰国社区环境中有亚临床抑郁的老年人的抑郁、压力和焦虑。未来的研究应评估 BA 在不同人群中的长期有效性。