两名患有阑尾低级别黏液性腹膜癌的一级亲属的生殖系和体细胞基因改变。
Germline and somatic genetic alterations in two first-degree relatives with appendiceal low-grade mucinous carcinoma peritonei.
作者信息
King Mary Caitlin, Munoz-Zuluaga Carlos, Ledakis Panayotis, Studeman Kimberley, Sittig Michelle, Gushchin Vadim, Sardi Armando
机构信息
The Institute for Cancer Care Mercy Medical Center Baltimore MD USA.
Department of Pathology Mercy Medical Center Baltimore MD USA.
出版信息
Clin Case Rep. 2020 Sep 29;8(12):3168-3177. doi: 10.1002/ccr3.3338. eCollection 2020 Dec.
Abstract
Comparing genetic mutations of first-degree relatives with appendiceal pseudomyxoma peritonei may explain clinical outcomes and disease pathogenesis. Molecular profiling of mucinous tumors may identify improved treatments to traditional chemotherapy.
摘要
比较腹膜假黏液瘤一级亲属的基因突变可能有助于解释临床结果和疾病发病机制。黏液性肿瘤的分子图谱分析可能会找到比传统化疗更好的治疗方法。
Zotero 插件