Leigh R J, Rushton D N, Thurston S E, Hertle R W, Yaniglos S S
Department of Neurology, University Hospitals, Cleveland, Ohio 44106.
Neurology. 1988 Jan;38(1):122-7. doi: 10.1212/wnl.38.1.122.
We studied the effects of variable amounts of artificial retinal image stabilization (RIS) upon oscillopsia and visual acuity in eight patients with acquired nystagmus due to neurologic disease. We measured horizontal and vertical eye movements with the magnetic search coil technique and used these electronic signals to control the position of a visual stimulus on a screen in front of the patient. We also used an optical device to stabilize images of the real world upon the retina. During electronic stabilization, RIS was progressively increased until oscillopsia was abolished; this was achieved in all eight patients and corresponded to retinal image drift of 5 degrees/sec or less. In five patients with downbeat nystagmus, further increases in RIS caused the oscillopsia to reappear, but in the opposite direction. Electronic stabilization also improved visual acuity in four of five patients; the limitation of improvement could be related to coexistent visual system defects. Using electronic feedback, we could measure the range of RIS that any individual required to abolish oscillopsia; from this measurement, the components of the optical device that were best suited to provide a stable field of vision could be calculated.
我们研究了不同程度的人工视网膜图像稳定（RIS）对8例因神经系统疾病导致后天性眼球震颤患者的视振荡和视力的影响。我们使用磁搜索线圈技术测量水平和垂直眼动，并利用这些电子信号控制患者面前屏幕上视觉刺激的位置。我们还使用一种光学装置来稳定真实世界在视网膜上的图像。在电子稳定过程中，RIS逐渐增加，直至视振荡消失；所有8例患者均实现了这一点，且对应视网膜图像漂移速度为5度/秒或更低。在5例下跳性眼球震颤患者中，RIS进一步增加导致视振荡再次出现，但方向相反。电子稳定还改善了5例患者中4例的视力；改善受限可能与并存的视觉系统缺陷有关。利用电子反馈，我们可以测量任何个体消除视振荡所需的RIS范围；通过该测量，可以计算出最适合提供稳定视野的光学装置组件。
