McMillan J A, Tristram D A, Weiner L B, Higgins A P, Sandstrom C, Brandon R
Department of Pediatrics, State University of New York Health Science Center, Syracuse 13210.
Pediatrics. 1988 Jan;81(1):22-6.
To assess the possibility that clinical data available at the time of hospital admission for patients with respiratory syncytial virus infection could predict the length of hospitalization without antiviral therapy, the charts of all 102 patients admitted with laboratory documented respiratory syncytial virus infection during 1982 to 1985 were reviewed. Two thirds (65) of the patients remained hospitalized greater than three days. Prolonged hospitalization could have been predicted for 40 of the 65 patients (61.5%) based on the need for intubation and ventilation on admission (14 patients) or the presence of underlying cardiac or respiratory disease (28 patients). Of the infants hospitalized when they were less than 2 months of age, 40% required intubation and mechanical ventilation, although only 16% had underlying cardiac or respiratory disease. Mechanical ventilation was required at the time of admission or subsequently for 14% (5/36) of the 2- to 4-month-old infants with respiratory syncytial virus infection. Among the 56 patients without underlying cardiac or respiratory disease who did not require intubation at the time of admission, 25 (45%) remained hospitalized longer than three days (mean hospital stay for these 25 patients, regardless of age, was six days). Neither the respiratory rate nor the presence or absence of fever on admission was useful in predicting the likelihood of a longer hospital stay for the patients who did not require intubation. In addition, none of the initial laboratory data, including the WBC count, the percentage of band forms or polymorphonuclear leukocytes, the presence or absence of hypoxia, or the chest x-ray film findings could be correlated with a longer or shorter duration of hospitalization.(ABSTRACT TRUNCATED AT 250 WORDS)
为评估呼吸道合胞病毒感染患者入院时的临床数据能否预测无抗病毒治疗情况下的住院时长,我们回顾了1982年至1985年间102例实验室确诊为呼吸道合胞病毒感染的住院患者病历。三分之二(65例)患者住院时间超过三天。基于入院时需要插管和通气(14例患者)或存在基础心脏或呼吸系统疾病(28例患者),65例患者中有40例(61.5%)可能会出现住院时间延长。小于2个月的婴儿住院时,40%需要插管和机械通气,尽管只有16%有基础心脏或呼吸系统疾病。2至4个月的呼吸道合胞病毒感染婴儿中,14%(5/36)在入院时或之后需要机械通气。在56例无基础心脏或呼吸系统疾病且入院时无需插管的患者中,25例(45%)住院时间超过三天(这25例患者,无论年龄,平均住院时间为六天)。入院时的呼吸频率以及是否发热,对于预测无需插管患者住院时间延长的可能性均无帮助。此外,包括白细胞计数、杆状核或多形核白细胞百分比、是否存在缺氧或胸部X光片结果在内的初始实验室数据,均与住院时间长短无关。(摘要截选于250词)