Webb W R, Stein M G, Finkbeiner W E, Im J G, Lynch D, Gamsu G
Department of Radiology, University of California School of Medicine, San Francisco 94143-0628.
Radiology. 1988 Jan;166(1 Pt 1):81-7. doi: 10.1148/radiology.166.1.3336706.
High-resolution computed tomography (CT) scans of 12 isolated, inflated, fresh lungs obtained at autopsy were compared with thin, paper-mounted lung sections obtained at the same levels. In six lungs considered intrinsically normal, high-resolution CT showed normal interlobular septa and pulmonary arteries in the lobular core, but lobular bronchioles were not visible. Edematous fluid resulted in thickening and increased visibility of interlobular septa. In three emphysematous lungs, high-resolution CT accurately demonstrated the degree of emphysema and suggested its centrilobular nature. In two lungs with honeycombing, cysts lined by fibrosis were easily seen on high-resolution CT scans. In less severely involved areas, septal thickening and intralobular fibrosis were seen on high-resolution CT scans, but small (1 mm) cysts were invisible. High-resolution CT was able to demonstrate some features of the normal secondary pulmonary lobule and structural alterations produced by various diseases.
对12例尸检时获取的孤立、充气新鲜肺脏进行高分辨率计算机断层扫描（CT），并与在相同层面获取的薄纸装裱肺切片进行比较。在6例被认为本质上正常的肺脏中，高分辨率CT显示小叶核心的小叶间隔和肺动脉正常，但小叶细支气管不可见。水肿液导致小叶间隔增厚且可见度增加。在3例肺气肿肺脏中，高分辨率CT准确显示了肺气肿的程度并提示其小叶中心型性质。在2例有蜂窝状改变的肺脏中，高分辨率CT扫描很容易看到由纤维化衬里的囊肿。在受累较轻的区域，高分辨率CT扫描可见间隔增厚和小叶内纤维化，但小（1毫米）囊肿不可见。高分辨率CT能够显示正常次级肺小叶的一些特征以及各种疾病所产生的结构改变。
