Megibow A J, Bosniak M A, Ho A G, Beller U, Hulnick D H, Beckman E M
Department of Radiology, New York University Medical Center, NY 10016.
Radiology. 1988 Feb;166(2):341-5. doi: 10.1148/radiology.166.2.3336709.
Computed tomographic (CT) studies in 39 patients with advanced ovarian carcinoma were retrospectively evaluated to assess their accuracy in detection of persistent or recurrent disease as seen at second-look laparotomy (SLL). Twenty patients were studied before June 1983 (group 1), and 19 patients were studied afterward (group 2). There were 16 true-positive, ten true-negative, two false-positive, and 11 false-negative examinations. Five false-negative studies resulted from microscopic disease found at SLL. In group 1, there were eight false-negative studies. In five, macroscopic disease was not recognized. In group 2, there were three false-negative studies; in one, macroscopic disease was not recognized. Statistical analysis showed an observable improvement in the accuracy in group 2. The differences included use of faster scanners, routine use of thin sections for the pelvis, and air-contrast colonic opacification in group 2. These results suggest that carefully performed scanning on state-of-the-art equipment may have a higher accuracy in documenting persistent or recurrent macroscopic tumor.
对39例晚期卵巢癌患者的计算机断层扫描（CT）研究进行回顾性评估，以评估其在检测二次探查剖腹术（SLL）时所见的持续性或复发性疾病方面的准确性。20例患者在1983年6月之前接受研究（第1组），19例患者之后接受研究（第2组）。有16例假阳性、10例假阴性、2例假阳性和11例假阴性检查。5例假阴性研究是由于SLL时发现的微小疾病。在第1组中，有8例假阴性研究。其中5例未识别出宏观疾病。在第2组中，有3例假阴性研究；其中1例未识别出宏观疾病。统计分析显示第2组的准确性有明显提高。差异包括第2组使用了更快的扫描仪、常规对骨盆使用薄层扫描以及空气对比结肠造影。这些结果表明，在最先进的设备上进行仔细扫描，在记录持续性或复发性宏观肿瘤方面可能具有更高的准确性。
