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索非亚老年青光眼患者的治疗。

Treatment of glaucoma among elderly patients in Sofia.

机构信息

Medical University of Sofia, Bulgaria.

Department of Ophthalmology, Alexandrovska University Hospital, Sofia, Bulgaria.

出版信息

Rom J Ophthalmol. 2020 Oct-Dec;64(4):404-409. doi: 10.22336/rjo.2020.62.

Abstract

To analyze therapy of glaucoma among the elderly population, 65 years old and above, in Sofia city, the capital of Bulgaria. Two prophylactic ophthalmic campaigns were realized in the summer of 2016 and 2017, in Sofia city. All patients passed thorough ophthalmic examinations and filled pen-and-paper questionnaires. The results and files were collected and statistically analyzed to estimate current antiglaucoma therapy among the elderly citizens of Sofia city. The predominant number of persons who were diagnosed with glaucoma, was treated with conservative monotherapy. Prostaglandin analogues have been prescribed to more than half of the patients in both studies. Fixed combinations have been used in 86% of the cases who needed combined therapy with two substances and in 100% of those with three medications. The therapeutic scheme used for treating glaucoma among elderly citizens of Sofia city is similar and corresponding to practice worldwide. Conservative monotherapy is used in mean 45%. When combined therapy is necessary, fixed combinations are predominantly prescribed with a target to minimize adverse events and to ensure better patients' compliance. A tendency of usage of preservative-free formulas to benefit patients' eye health has been noticed. POSE = prophylactic ophthalmic screening among elderly people, GSW = glaucoma screening week, EGS = European Glaucoma Society, PEX= pseudoexfoliative syndrome, PGAs = Prostaglandin analogues, CAIs = Carbonic Anhydrase Inhibitors.

摘要

为了分析保加利亚首都索非亚市 65 岁及以上老年人的青光眼治疗情况,在 2016 年和 2017 年的夏季,该市进行了两次预防性眼科活动。所有患者都接受了全面的眼科检查,并填写了纸笔问卷。收集并对结果和档案进行了统计分析,以评估索非亚市老年公民目前的抗青光眼治疗情况。被诊断为青光眼的患者中,绝大多数接受了保守的单一疗法治疗。在这两项研究中,超过一半的患者被开了前列腺素类似物,而在需要两种药物联合治疗的病例中,有 86%使用了固定组合,在需要三种药物联合治疗的病例中,有 100%使用了固定组合。索非亚市老年公民的青光眼治疗方案与全球实践相似并相符。保守的单一疗法的使用率平均为 45%。当需要联合治疗时,主要开固定组合,以尽量减少不良反应,并确保更好的患者依从性。我们注意到,为了患者的眼部健康,人们倾向于使用不含防腐剂的配方。POSE = 老年人预防性眼科筛查,GSW = 青光眼筛查周,EGS = 欧洲青光眼学会,PEX = 假性剥脱综合征,PGAs = 前列腺素类似物,CAIs = 碳酸酐酶抑制剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5152/7739016/2ed4d9e9f558/RomJOphthalmol-64-404-g001.jpg

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