Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Federal University of Rio de Janeiro-UFRJ, Rio de Janeiro, Brazil.
Department of Health I, Southwest Bahia State University, Jequié, Bahia, Brazil.
Eur J Orthod. 2021 Apr 3;43(2):208-214. doi: 10.1093/ejo/cjaa075.
The maxillary lateral incisor is one of the teeth most likely to suffer agenesis, resulting in spacing between the central incisor and the canine.
To compare maxillary lateral incisor agenesis with space closure treatment versus non-treatment based on measurements of the self-perceived oral-health-related quality of life (OHRQoL) and self-esteem of the participants.
A total of 44 people, aged 17-49 years, with missing lateral incisors were randomly assigned to two groups (n = 22 in each)-a treated group in which the space was orthodontically closed (TG) and a control group that remained untreated (CG). Randomization was performed by a researcher who was not involved in the clinical part of the study. The outcomes were assessed using the Oral Health Impact Profile and Rosenberg's Self-Esteem Scale, which were applied before (phase 1) and after (phase 2) the orthodontic treatment in the TG, and at baseline (phase 1) and 12 months after (phase 2) in the CG. All the data were blindly evaluated, supporting the single-blinded design of the study.
All participants finished the randomized controlled trial, and the demographic characteristics were similar between the groups. In phase 1, the levels of self-esteem and OHRQoL at baseline were similar (P = 0.079, P = 0.693, respectively). In phase 2, the self-esteem scores of the CG decreased and the OHRQoL increased (P = 0.005, P < 0.001, respectively), while self-esteem increased in the TG and the OHRQoL decreased (P < 0.001). The CG had lower scores than the TG for self-esteem, but the opposite was observed for OHRQoL (P < 0.001).
Information bias may have occurred. Since the questionnaires could not have been applied at the same time in both groups, the time difference between the two assessments may have led to random and systematic error.
The spacing resulting from missing maxillary lateral incisors had a negative impact on the OHRQoL and self-esteem of the participants, while orthodontically closing those spaces had a positive impact on those aspects.
This study was not registered.
The protocol was not published before trial commencement.
上颌侧切牙是最容易发生先天缺失的牙齿之一，导致中切牙和尖牙之间出现间隙。
基于参与者自我感知的口腔健康相关生活质量（OHRQoL）和自尊的测量，比较上颌侧切牙缺失的患者进行间隙关闭治疗与不治疗的效果。
共 44 名年龄在 17-49 岁之间、缺失侧切牙的患者被随机分为两组（每组 22 名）-接受正畸关闭间隙治疗的治疗组（TG）和未治疗的对照组（CG）。随机分组由不参与研究临床部分的研究人员进行。采用口腔健康影响程度量表（OHIP-14）和罗森伯格自尊量表（RSE）评估结果，在 TG 的正畸治疗前（阶段 1）和治疗后（阶段 2），以及 CG 的基线（阶段 1）和治疗后 12 个月（阶段 2）进行评估。所有数据均进行了盲法评估，支持研究的单盲设计。
所有参与者均完成了随机对照试验，且两组的人口统计学特征相似。在阶段 1 时，基线时的自尊和 OHRQoL 水平相似（P = 0.079，P = 0.693）。在阶段 2 时，CG 的自尊评分下降，OHRQoL 升高（P = 0.005，P < 0.001），而 TG 的自尊评分升高，OHRQoL 下降（P < 0.001）。CG 的自尊评分低于 TG，但 OHRQoL 评分则相反（P < 0.001）。
可能存在信息偏倚。由于两组不能同时应用问卷，两次评估之间的时间差异可能导致随机和系统误差。
上颌侧切牙缺失导致的间隙会对参与者的 OHRQoL 和自尊产生负面影响，而正畸关闭这些间隙则对这些方面产生积极影响。
本研究未注册。
方案在试验开始前未发表。
