造血细胞移植中的端粒长度。
Telomere length in hematopoietic cell transplant.
机构信息
National Cancer Institute.
出版信息
Blood. 2020 Dec 24;136(26):2972-2973. doi: 10.1182/blood.2020008547.
Abstract
In this issue of , Myllymäki et al evaluated the role of pretransplant leukocyte telomere length (LTL) on survival outcomes in patients with myelodysplastic syndrome (MDS). The authors found associations between recipient short LTL and poor overall survival and high risk of nonrelapse mortality (NRM) after unrelated donor hematopoietic cell transplant (HCT).
摘要
在本期 中，Myllymäki 等人评估了骨髓增生异常综合征（MDS）患者移植前白细胞端粒长度（LTL）对生存结果的作用。作者发现，在无关供体造血细胞移植（HCT）后，受体端粒较短与总生存率差和非复发死亡率（NRM）高相关。
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