Abdelwahab Mohamed, Patel Priyesh N, Most Sam P
Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology - Head & Neck Surgery, Stanford University School of Medicine, Stanford, California.
Department of Otolaryngology - Head & Neck Surgery, Mansoura University, Faculty of Medicine, Mansoura, Egypt.
Facial Plast Surg. 2020 Dec;36(6):727-736. doi: 10.1055/s-0040-1721113. Epub 2020 Dec 24.
Reconstructive procedures in the head and neck can be a surgical challenge owing to the complex anatomical and physiological structure. Different locoregional and microvascular flaps are used for various defects to improve both function and cosmesis. Subjective clinical findings have been the mainstay for perfusion monitoring; however, areas of borderline perfusion are much more difficult to assess clinically. Multiple technologies that offer objective perfusion assessment have been developed to improve surgical outcomes. Indocyanine green (ICG) angiography has gained popularity owing to its minimal invasiveness and increased sensitivity and specificity in assessing flap perfusion particularly in the head and neck. It has been extensively used in free flaps, pedicled flaps (including nasal reconstruction), facelift procedures, random flaps, skull base reconstruction, and pharyngocutaneous fistula prediction. Its perioperative use has provided valuable qualitative and quantitative data that aid our understanding of flap hemodynamics. Clinically, this impacted decision-making in flap design, harvest, inset, and precocious salvage interventions. Though increased cost and intraoperative time could be limitations, cost-effectiveness studies have supported its use, particularly in high-risk individuals. Limitations include the lack of standardized dosing and consistent methodology agreement for data analysis. Future studies should involve larger cohorts and multi-institute studies to overcome such limitations.
由于头颈部复杂的解剖和生理结构,头颈部的重建手术可能是一项外科挑战。不同的局部和微血管皮瓣用于各种缺损,以改善功能和美观。主观临床发现一直是灌注监测的主要依据;然而,临界灌注区域在临床上更难评估。为了改善手术效果,已经开发了多种提供客观灌注评估的技术。吲哚菁绿(ICG)血管造影因其微创性以及在评估皮瓣灌注方面,尤其是在头颈部,具有更高的敏感性和特异性而受到欢迎。它已广泛应用于游离皮瓣、带蒂皮瓣(包括鼻再造)、面部提升手术、随意皮瓣、颅底重建以及咽皮肤瘘预测。其围手术期的应用提供了有价值的定性和定量数据,有助于我们理解皮瓣血流动力学。在临床上,这影响了皮瓣设计、切取、植入和早期挽救干预的决策。尽管成本增加和手术时间延长可能是限制因素,但成本效益研究支持其使用,特别是在高危个体中。局限性包括缺乏标准化给药以及数据分析方法的一致性。未来的研究应纳入更大的队列并开展多机构研究以克服这些局限性。