Nicolas Brault, Interact UP 2018.C102, UniLaSalle, Beauvais, France.
Mohit Saxena, Sup'Biotech Paris, Villejuif, France.
J Eval Clin Pract. 2021 Jun;27(3):513-519. doi: 10.1111/jep.13528. Epub 2020 Dec 23.
RATIONALE, AIMS AND OBJECTIVES: Artificial intelligence and big data are more and more used in medicine, either in prevention, diagnosis or treatment, and are clearly modifying the way medicine is thought and practiced. Some authors argue that the use of artificial intelligence techniques to analyze big data would even constitute a scientific revolution, in medicine as much as in other scientific disciplines. Moreover, artificial intelligence techniques, coupled with mobile health technologies, could furnish a personalized medicine, adapted to the individuality of each patient. In this paper we argue that this conception is largely a myth: what health professionals and patients need is not more data, but data that are critically appraised, especially to avoid bias.
In this historical and conceptual article, we focus on two main problems: first, the data and the problem of its validity; second, the inference drawn from the data by AI, and the establishment of correlations through the use of algorithms. We use examples from the contemporary use of mobile health (mHealth), i.e. the practice of medicine and public health supported by mobile or wearable devices such as mobile phones or smart watches.
We show that the validity of the data and of the inferences drawn from these mHealth data are likely to be biased. As biases are insensitive to the size of the sample, even if the sample is the whole population, artificial intelligence and big data cannot avoid biases and even tend to increase them.
The large amount of data thus appears rather as a problem than a solution. What contemporary medicine needs is not more data or more algorithms, but a critical appraisal of the data and of the analysis of the data. Considering the history of epidemiology, we propose three research priorities concerning the use of artificial intelligence and big data in medicine.
背景、目的和目标:人工智能和大数据在医学领域的应用越来越广泛,无论是在预防、诊断还是治疗方面,它们显然正在改变人们对医学的思考和实践方式。一些作者认为,使用人工智能技术来分析大数据甚至将构成医学乃至其他科学学科的一场科学革命。此外,人工智能技术与移动健康技术相结合,可以提供个性化医疗,以适应每个患者的个体差异。本文认为,这种观念在很大程度上是一种神话:健康专业人员和患者需要的不是更多的数据,而是经过批判性评估的数据,尤其是为了避免偏差。
在这篇历史和概念性文章中,我们重点关注两个主要问题:首先是数据及其有效性问题;其次是人工智能从数据中得出的推论,以及通过使用算法建立相关性。我们使用当代移动健康(mHealth)的实例来说明问题,即通过移动或可穿戴设备(如手机或智能手表)支持的医学和公共卫生实践。
我们表明,这些 mHealth 数据的数据有效性和从这些数据中得出的推论很可能存在偏差。由于偏差对样本大小不敏感,即使样本是整个人群,人工智能和大数据也无法避免偏差,甚至可能加剧偏差。
因此,大量的数据与其说是解决方案,不如说是一个问题。当代医学需要的不是更多的数据或更多的算法,而是对数据和数据分析的批判性评估。考虑到流行病学的历史,我们针对人工智能和大数据在医学中的应用提出了三个研究重点。