西地那非被滥用产生致幻效果？一例报告。

Sildenafil Misuse for its Psychoactive Properties? A Case Report.

机构信息

National Drug Dependence Treatment Centre and Department of Psychiatry, All India Institute of Medical Sciences, New Delhi - 29, India (RM, SS, TT, RB, RR); Department of Psychiatry and Drug De-addiction and Treatment Center, All India Institute of Medical Sciences, Bhubaneswar, India (AP).

出版信息

J Addict Med. 2021;15(6):522-524. doi: 10.1097/ADM.0000000000000805.

DOI:10.1097/ADM.0000000000000805

PMID:33369975

Abstract

Sildenafil is a widely used drug for the treatment of erectile dysfunction in a dosage ranging from 50 to 100 mg per day. Recreational use is reported among youth for its sexual function enhancing effects. To date, however, no study has reported the use of sildenafil for its nonsexual, psychoactive effects. We report a case of a 38-year-old male with opioid and sedative use disorder who self-administered sildenafil orally in a dose of up to 2000 mg per day for its psychoactive effects (primarily) for 10 years before seeking treatment and discuss the literature relevant to the case.

摘要

西地那非是一种广泛用于治疗勃起功能障碍的药物，每日剂量为 50 至 100 毫克。有报道称，年轻人会滥用该药来增强性能力。然而，迄今为止，尚无研究报告西地那非具有非性、精神活性作用。我们报告了 1 例 38 岁男性，患有阿片类药物和镇静剂使用障碍，10 年来每天口服高达 2000 毫克的西地那非以获得精神活性作用（主要是），随后寻求治疗，并讨论了与该病例相关的文献。