Blumenthal J A, Rejeski W J, Walsh-Riddle M, Emery C F, Miller H, Roark S, Ribisl P M, Morris P B, Brubaker P, Williams R S
Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27710.
Am J Cardiol. 1988 Jan 1;61(1):26-30. doi: 10.1016/0002-9149(88)91298-2.
The effects of the intensity of exercise training on cardiorespiratory variables were investigated in a consecutive series of men with recent (median 8 weeks) acute myocardial infarction. Forty-five patients were randomly assigned either to a high- (65 to 75% maximum oxygen consumption rate [VO2max]) or to a low-intensity (less than 45% VO2max) exercise group. Patients engaged in medically supervised aerobic training 3 sessions a week for 12 weeks. With training, mean VO2max significantly increased by 11% (2.09 to 2.31 liters/min) within the high group and by 14% (1.93 to 2.21 liters/min) within the low group. Differences between groups were not statistically significant. Both groups also had comparable changes in heart rate, blood pressure and double-product at submaximal and maximal workloads. Analysis of blood lipids revealed that both groups experienced a significant increase in high density lipoprotein cholesterol. There were no significant changes in total serum cholesterol or triglycerides. These findings suggest that within an unselected population of patients after acute myocardial infarction referred for cardiac rehabilitation, low- and high-intensity exercise training produces relatively similar changes in cardiorespiratory variables during the initial 3 months of exercise training.
在一系列近期（中位时间8周）发生急性心肌梗死的男性患者中，研究了运动训练强度对心肺变量的影响。45名患者被随机分为高强度（最大耗氧率[VO2max]的65%至75%）或低强度（低于VO2max的45%）运动组。患者在医学监督下进行每周3次、为期12周的有氧训练。经过训练，高强度组的平均VO2max显著增加了11%（从2.09升/分钟增至2.31升/分钟），低强度组增加了14%（从1.93升/分钟增至2.21升/分钟）。两组之间的差异无统计学意义。在次最大和最大负荷下，两组的心率、血压和双乘积也有类似变化。血脂分析显示，两组的高密度脂蛋白胆固醇均显著升高。总血清胆固醇或甘油三酯无显著变化。这些发现表明，在因心脏康复而接受治疗的急性心肌梗死患者这一未经过筛选的人群中，低强度和高强度运动训练在运动训练的最初3个月内，会使心肺变量产生相对相似的变化。
