Rowland M G, Rowland S G, Cole T J
Medical Research Council (MRC) Laboratories, Fajara, The Gambia.
Am J Clin Nutr. 1988 Jan;47(1):134-8. doi: 10.1093/ajcn/47.1.134.
To determine the relationship between growth and morbidity in the first 2 y of life, we studied a cohort of 126 newborns in a Gambian township. Mean weight-for-age exceeded the National Center for Health Statistics (NCHS) standards in the first half of infancy but there was a mean deficit of 1.2 kg by age 1 y. Only two diseases contributed significantly to weight faltering: diarrheal diseases were estimated to cause one-half of the deficit and lower respiratory tract infections (LRTI) one-quarter. LRTI reduced weight gain in young children by 14.7 g/d of infection and diarrheal diseases in weaning infants by 14.4 g/d. Diarrhea had no significant impact on the growth of exclusively breast-fed infants. Growth velocity was normal in the second year of life, despite continuing infections.
为了确定生命最初2年生长与发病之间的关系，我们对冈比亚一个小镇的126名新生儿队列进行了研究。在婴儿期的前半年，平均年龄别体重超过了美国国家卫生统计中心（NCHS）的标准，但到1岁时平均体重不足1.2千克。只有两种疾病对体重增长迟缓有显著影响：腹泻病估计导致了一半的体重不足，下呼吸道感染（LRTI）导致了四分之一。下呼吸道感染使幼儿的体重增长每天减少14.7克，断奶婴儿的腹泻病使体重增长每天减少14.4克。腹泻对纯母乳喂养婴儿的生长没有显著影响。尽管持续感染，但在生命的第二年生长速度正常。
