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Int J Angiol. 2013 Sep;22(3):149-54. doi: 10.1055/s-0033-1348885.
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Contrast-induced neurotoxicity after coronary angiography.冠状动脉造影术后对比剂诱导的神经毒性
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Clinical pharmacology, uses, and adverse reactions of iodinated contrast agents: a primer for the non-radiologist.碘造影剂的临床药理学、用途和不良反应:非放射科医师入门。
Mayo Clin Proc. 2012 Apr;87(4):390-402. doi: 10.1016/j.mayocp.2012.01.012.
5
Iodinated contrast media and their adverse reactions.碘化造影剂及其不良反应。
J Nucl Med Technol. 2008 Jun;36(2):69-74; quiz 76-7. doi: 10.2967/jnmt.107.047621. Epub 2008 May 15.
6
Intravascular iodinated contrast media and the anaesthetist.血管内碘化造影剂与麻醉医生。
Anaesthesia. 2008 Jun;63(6):626-34. doi: 10.1111/j.1365-2044.2008.05479.x.
7
Myelography complications and current practice patterns.脊髓造影并发症及当前实践模式。
AJR Am J Roentgenol. 2005 Sep;185(3):768-71. doi: 10.2214/ajr.185.3.01850768.
8
X-ray contrast media--an overview.X射线造影剂——概述
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9
Metformin hydrochloride in patients undergoing myelography.接受脊髓造影术患者中的盐酸二甲双胍
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10
Aseptic meningoencephalitis after iopamidol myelography.碘帕醇脊髓造影术后无菌性脑膜脑炎。
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鞘内碘对比剂引起的短暂性脊髓休克。

Intrathecal iodinated contrast-induced transient spinal shock.

机构信息

Jinnah Sindh Medical University, Karachi, Sindh, Pakistan.

Liaquat University of Medical and Health Sciences, Jamshoro, Sindh, Pakistan.

出版信息

BMJ Case Rep. 2020 Dec 21;13(12):e237610. doi: 10.1136/bcr-2020-237610.

DOI:10.1136/bcr-2020-237610
PMID:33370945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7754623/
Abstract

Transient spinal shock is a previously unreported complication of intrathecal contrast. A 63-year-old man presented with the chief complaint of worsening back pain. Computed topography of lumbar spine without contrast showed a lytic lesion. After international normalized ratio (INR) correction, patient was sent for CT myelogram. After intrathecal contrast injection, the patient dropped his blood pressure profoundly and developed clinical manifestations of spinal shock. Emergent intravenous bolus fluids were initiated resulting in improvement in blood pressure. Patient's spinal shock resolved within hours. CT myelogram was normal except previously known lytic lesion. It was concluded that the transient shock was most likely due to contrast injection. We believe that this is the first reported case of transient spinal shock following CT myelogram using water-soluble iodinated non-ionic contrast agent administered intrathecally.

摘要

一过性脊髓休克是鞘内对比剂一个以前未报道的并发症。一位 63 岁男性以背痛加重为主诉就诊。腰椎 CT 平扫未见异常。国际标准化比值(INR)纠正后,患者行 CT 脊髓造影。鞘内注射对比剂后,患者血压明显下降,并出现脊髓休克的临床表现。立即静脉推注液体,血压改善。数小时后患者脊髓休克缓解。CT 脊髓造影除已知溶骨性病变外无异常。结论认为,短暂性休克最可能是由于对比剂注射引起。我们认为这是首例报告的 CT 脊髓造影使用水溶性碘非离子型对比剂鞘内给药后出现短暂性脊髓休克的病例。