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旋转血栓弹性测定术在全髋关节翻修术中的应用(病例对照研究)。

Utility of rotational thromboelastometry in total hip replacement revision surgery (case-control study).

机构信息

Department of Anaesthesiology and Intensive Care Medicine, Second Faculty of Medicine, Charles University and Motol University Hospital.

出版信息

Medicine (Baltimore). 2020 Dec 18;99(51):e23553. doi: 10.1097/MD.0000000000023553.

DOI:10.1097/MD.0000000000023553
PMID:33371082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7748196/
Abstract

Total hip replacement revision surgery is accompanied by significant blood loss. Using rotational thrombelastometry (ROTEM) perioperatively to diagnose coagulopathy may help to provide rapid aimed therapy and thus decrease blood loss and the consumption of transfusion products. The aim of this case-control study was to find out whether point of care using of ROTEM may reduce blood loss and the consumption of blood transfusion products in hip replacement revision surgery.Data were prospectively collected from patients who underwent hip replacement revision surgery in the period 2017 to 2018 when the management of bleeding and coagulopathy was based on the results of ROTEM. Data were compared with a group of historical controls for the period 2015 to 2016 when bleeding and coagulopathy management was not based on ROTEM results. The consumption of blood transfusion products and perioperative blood loss were compared between the groups.The total number of analyzed patients was 90. Forty five patients were analyzed in the ROTEM group and the same number of patients were analyzed in the non-ROTEM group. Significantly decreased perioperative consumption of fresh frozen plasma and packed red blood cells was found in the ROTEM, as well as decreased perioperative blood loss comparing to non-ROTEM group. All data were statistically different with P < .05.Perioperative management of bleeding and coagulopathy based on the results of ROTEM during hip replacement revision surgery seems to help to decrease perioperative blood loss and the consumption of blood transfusion products, especially fresh frozen plasma.

摘要

全髋关节置换翻修术会伴随大量失血。围手术期使用旋转血栓弹性测定仪(ROTEM)诊断凝血功能障碍有助于提供快速靶向治疗,从而减少失血和输血产品的消耗。本病例对照研究旨在探讨髋关节置换翻修术中即时使用 ROTEM 是否可以减少失血量和输血产品的消耗。

2017 年至 2018 年期间,当出血和凝血功能障碍的管理基于 ROTEM 结果时,前瞻性地收集了接受髋关节置换翻修术的患者的数据。将数据与 2015 年至 2016 年期间未基于 ROTEM 结果管理出血和凝血功能障碍的历史对照组进行比较。比较两组间输血产品的消耗和围手术期失血量。

共分析了 90 例患者。ROTEM 组分析了 45 例患者,非 ROTEM 组也分析了 45 例患者。ROTEM 组的新鲜冷冻血浆和浓缩红细胞的围手术期消耗显著减少,与非 ROTEM 组相比,围手术期失血量也减少。所有数据均具有统计学差异(P<0.05)。

髋关节置换翻修术围手术期基于 ROTEM 结果管理出血和凝血功能似乎有助于减少围手术期失血量和输血产品的消耗,尤其是新鲜冷冻血浆。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f2/7748196/1efb61f323fd/medi-99-e23553-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f2/7748196/ae6e5e14d6a2/medi-99-e23553-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f2/7748196/1efb61f323fd/medi-99-e23553-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f2/7748196/ae6e5e14d6a2/medi-99-e23553-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f2/7748196/1efb61f323fd/medi-99-e23553-g002.jpg

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