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妊娠期糖尿病患者及其血糖仪的使用是否比不使用血糖仪的患者有更好的妊娠结局?

Do patients with gestational diabetes mellitus and their own blood glucose meter have better pregnancy outcomes than those not using a glucose meter?

机构信息

Department of Gynecological and Health Care Guidance, Tianjin Women's and Children's Health Center.

Department of Gynecology, The Second Hospital of Tianjin Medical University, Tianjin, China.

出版信息

Medicine (Baltimore). 2020 Dec 18;99(51):e23793. doi: 10.1097/MD.0000000000023793.

Abstract

To compare pregnancy outcomes between patients with gestational diabetes mellitus (GDM) with and without their own blood glucose meter.We conducted a retrospective-cohort study of 835 women with GDM at the Second Hospital of Tianjin Medical University, Tianjin, China from 1 January 2016 to 31 December 2018. Perinatal outcomes of these patients were monitored and collected in the Tianjin Maternal and Child Health System. Each patient was advised by a certified clinical nutritionist regarding dietary analysis and lifestyle recommendations. All pregnant women with GDM were divided into the following 2 groups according to whether they had their own blood glucose meter: women with self-measured blood glucose levels with a routine obstetric examination in the study group (n = 424); and those with non-self-measured blood glucose levels with a double obstetric examination in the control group (n = 411). Maternal and fetal pregnancy outcomes were compared between these 2 groups. According to different self-management modes, the women were also divided into eight subgroups to compare blood sugar control and compliance with recommended insulin therapy.The cesarean section rate was significantly lower in the study group than in the control group (P < .05). The prevalence of large-for-gestational age (P < .05) and macrosomia was significantly lower in the study group than in the control group (both P < .05). The prevalence of appropriate-for-gestational age was significantly higher in the study group than in the control group (P < .05). Birth weight was significantly lower in the study group than in the control group (P < .05). The mean times for blood sugar control and from the doctor recommendation for insulin treatment to the patient compliance in the study group were significantly shorter than those in the control group (both P < .05). The proportion of insulin required in the study group was significantly lower than that in the control group (P < .05). There were no significant differences in the time of controlling blood sugar and compliance among the 4 subgroups of the study group. However, subgroups with a dietary diary in the control group were better.Self-monitoring blood sugar plus a routine obstetric examination can help patients with GDM control blood sugar, even without dietary diaries and treadmills. In addition to increasing the number of obstetric examinations, recording dietary diaries is helpful for controlling blood sugar in patients with GDM who are unwilling to measure blood sugar by themselves.

摘要

为了比较患有妊娠期糖尿病(GDM)的患者使用和不使用血糖仪时的妊娠结局。我们在中国天津市天津医科大学第二医院对 835 名 GDM 患者进行了回顾性队列研究,研究时间为 2016 年 1 月 1 日至 2018 年 12 月 31 日。通过天津市妇幼保健系统监测和收集这些患者的围产期结局。每位患者均由经过认证的临床营养师提供关于饮食分析和生活方式建议。所有 GDM 孕妇均根据是否拥有血糖仪分为以下 2 组:研究组中自我监测血糖水平并进行常规产科检查的孕妇(n=424);以及对照组中未自我监测血糖水平并进行双重产科检查的孕妇(n=411)。比较这 2 组孕妇的母婴妊娠结局。根据不同的自我管理模式,还将这些妇女分为 8 个亚组,以比较血糖控制情况和对推荐胰岛素治疗的依从性。研究组的剖宫产率明显低于对照组(P<0.05)。研究组中巨大儿(P<0.05)和巨大儿的发生率明显低于对照组(均 P<0.05)。研究组中适于胎龄儿的发生率明显高于对照组(P<0.05)。研究组的出生体重明显低于对照组(P<0.05)。研究组血糖控制时间和从医生建议胰岛素治疗到患者依从的时间均明显短于对照组(均 P<0.05)。研究组需要胰岛素的比例明显低于对照组(P<0.05)。研究组的 4 个亚组之间血糖控制和依从性的时间无明显差异。然而,对照组中有饮食日记的亚组更好。自我监测血糖加上常规产科检查有助于 GDM 患者控制血糖,即使没有饮食日记和跑步机也是如此。除了增加产科检查次数外,记录饮食日记对不愿意自我监测血糖的 GDM 患者控制血糖也有帮助。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2328/7748300/cfca8390933e/medi-99-e23793-g001.jpg

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