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Plasma levels of the active form of suPAR are associated with COVID-19 severity.

作者信息

Huang Mingxiang, Li Linlin, Shen Jianshan, Wang Yao, Wang Rui, Yuan Cai, Huang Mingdong, Jiang Longguang

机构信息

Department of Clinical Laboratory, Fuzhou Pulmonary Hospital of Fujian, Fuzhou, 350008, Fujian, China.

College of Chemistry, Fuzhou University, Fuzhou, 350116, Fujian, China.

出版信息

Crit Care. 2020 Dec 29;24(1):704. doi: 10.1186/s13054-020-03336-0.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f780/7771065/47e1d021b3c5/13054_2020_3336_Fig1_HTML.jpg

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本文引用的文献

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Soluble Urokinase Receptor (SuPAR) in COVID-19-Related AKI.
J Am Soc Nephrol. 2020 Nov;31(11):2725-2735. doi: 10.1681/ASN.2020060829. Epub 2020 Sep 22.
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COVID-19 and pneumonia: a role for the uPA/uPAR system.
Drug Discov Today. 2020 Aug;25(8):1528-1534. doi: 10.1016/j.drudis.2020.06.013. Epub 2020 Jun 18.
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An ELISA method detecting the active form of suPAR.
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Structure of human urokinase plasminogen activator in complex with its receptor.
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The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R.
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