经皮纤维松解术对轻中度腕管综合征的机械敏感性、残疾和神经传导研究的影响:一项随机对照试验的二次分析。
Effects of Diacutaneous Fibrolysis on Mechanosensitivity, Disability, and Nerve Conduction Studies in Mild to Moderate Carpal Tunnel Syndrome: Secondary Analysis of a Randomized Controlled Trial.
机构信息
University of Valladolid, Soria, Spain.
University of Zaragoza, Zaragoza, Spain.
出版信息
Phys Ther. 2021 Feb 4;101(2). doi: 10.1093/ptj/pzaa222.
OBJECTIVE
People diagnosed with carpal tunnel syndrome (CTS) have fibrosis between the soft, connective, and neural tissues that could worsen the compression of the median nerve. The diacutaneous fibrolysis (DF) technique may release tissue adhesions and increase the mobility of connective tissues. The purpose of this study was to compare the outcomes of DF in people with mild to moderate CTS on mechanosensitivity, disability, and nerve conduction studies.
METHODS
This was a secondary analysis of a double-blinded, randomized, placebo-controlled trial. Patients were recruited between April and September 2016 from the Department of Neurophysiology at the Hospital Miguel Servet, Zaragoza, Spain. Thirty-nine people (52 wrists) diagnosed with mild to moderate CTS were included. Participants were randomly assigned to either the DF group (n = 26) or the sham group (n = 26). Both groups received 5 therapy sessions, 2 sessions per week. Mechanosensitivity with the Upper Limb Neurodynamic Test 1, symptom severity and functional status with the Boston Carpal Tunnel Questionnaire, and median nerve sensory conduction velocity with nerve conduction studies were the outcomes measured. Assessments were recorded at baseline and after the intervention.
RESULTS
The DF group showed significant improvements in the following: mechanosensitivity, with 28.46 degrees of elbow extension range of motion (95% CI = 19.2-37.7); an increase of 1.0 point (95% CI = 0.7-1.4) for the Boston Carpal Tunnel Questionnaire symptom severity and functional status score; and sensory conduction velocity of median nerve, which improved to 5.8 m/s (95% CI = 2.5-9.2).
CONCLUSION
Participants with mild to moderate CTS experienced improvements in symptom severity, functional status, mechanosensitivity, and nerve conduction studies after 5 sessions of DF.
IMPACT
This study provides evidence of an approach based on soft and connective tissues around the median nerve in patients with CTS.
目的
患有腕管综合征(CTS)的人,其柔软的、结缔组织和神经组织之间存在纤维化,这可能会使正中神经受压更严重。皮肤切开纤维松解(DF)技术可能会释放组织粘连物并增加结缔组织的活动性。本研究旨在比较 DF 对轻度至中度 CTS 患者的机械敏感性、残疾和神经传导研究的结果。
方法
这是一项双盲、随机、安慰剂对照试验的二次分析。2016 年 4 月至 9 月,西班牙萨拉戈萨 Miguel Servet 医院神经生理学系招募了 39 名(52 只手腕)轻度至中度 CTS 患者。参与者被随机分配到 DF 组(n=26)或 sham 组(n=26)。两组均接受 5 次治疗,每周 2 次。使用上肢神经动力学测试 1 测量机械敏感性,使用波士顿腕管问卷测量症状严重程度和功能状态,使用神经传导研究测量正中神经感觉传导速度。在基线和干预后进行评估。
结果
DF 组在以下方面有显著改善:机械敏感性,肘部伸展活动范围增加 28.46 度(95%CI=19.2-37.7);波士顿腕管问卷症状严重程度和功能状态评分增加 1.0 分(95%CI=0.7-1.4);正中神经感觉传导速度提高至 5.8 m/s(95%CI=2.5-9.2)。
结论
患有轻度至中度 CTS 的患者在接受 5 次 DF 治疗后,症状严重程度、功能状态、机械敏感性和神经传导研究均有改善。
影响
本研究为 CTS 患者的正中神经周围软结缔组织提供了一种基于循证的治疗方法。