Blokhina N G, Smolianskaia A Z, Aledseev V M, Sokolova V D
Vopr Onkol. 1977;23(8):33-7.
The concentration of the active principle of ftorafur in blood and urine varied depending on the activity of metabolic processes in a patient, size and sensitivity of tumor, etc. The concentrations increased in repeat injections of the substance. The efficacy was related with the intensity of formation of active components, but is not dependent on the substance level dtermined in biological fluids of the organism.
呋氟尿嘧啶有效成分在血液和尿液中的浓度因患者代谢过程的活性、肿瘤大小和敏感性等因素而异。重复注射该物质时浓度会升高。疗效与活性成分的形成强度有关,但不取决于在生物体生物体液中测定的该物质水平。