Prodromidou Anastasia, Pandraklakis Anastasios, Rodolakis Alexandros, Thomakos Nikolaos
Department of Obstetrics and Gynecology, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Diagnostics (Basel). 2020 Dec 22;11(1):3. doi: 10.3390/diagnostics11010003.
Endometriosis is a common benign gynecological condition defined as the presence of endometrial tissue in tissues outside the uterine cavity. Apart from the common sites of endometriosis, rare sites other have also been reported including the liver, the thoracic cavity, the muscles, nerves, and more rarely in a patent Nuck canal. We aim to evaluate the clinical presentation, diagnostic features, and management of the Nuck endometriosis. A meticulous search of three electronic databases was performed until May 2020 for articles reporting cases of Nuck endometriosis. A total of 36 patients from 20 studies were analyzed. Median age of patients was 36 years with 33 women being of reproductive age. A right-sided lesion was identified in 30 cases (83.3%), while all patients suffer from a groin mass with cyclic pain in a proportion of 22%. All the patients finally underwent surgery for investigation of the lesion and fixation of the defect. Five cases of malignancy were detected at final pathology. All of them were alive with a median reported overall survival of 37 months. Nuck endometriosis should be included in the differential diagnosis of female patients with groin swelling. An evaluation by a gynecologist is important when endometriosis is suspected.
子宫内膜异位症是一种常见的良性妇科疾病，定义为子宫腔外组织中存在子宫内膜组织。除了子宫内膜异位症的常见部位外，也有报道称其罕见部位包括肝脏、胸腔、肌肉、神经，更罕见的是在未闭的Nuck管中。我们旨在评估Nuck管子宫内膜异位症的临床表现、诊断特征及治疗方法。截至2020年5月，我们对三个电子数据库进行了细致检索，以查找报告Nuck管子宫内膜异位症病例的文章。共分析了来自20项研究的36例患者。患者的中位年龄为36岁，其中33名女性处于育龄期。30例（83.3%）发现右侧病变，所有患者均有腹股沟肿块，其中22%伴有周期性疼痛。所有患者最终均接受手术以检查病变并修复缺损。最终病理检查发现5例恶性肿瘤。所有患者均存活，报告的中位总生存期为37个月。Nuck管子宫内膜异位症应纳入女性腹股沟肿胀患者的鉴别诊断中。怀疑患有子宫内膜异位症时，由妇科医生进行评估很重要。
