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三维（3D）培养模型在癌症研究、药物测试和免疫反应评估中的应用。

Three-Dimensional (3D) Culture Models in Cancer Investigation, Drug Testing and Immune Response Evaluation.

机构信息

Unit of MolecularOncology and Angiogenesis, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.

Division of Immunology, Transplants and Infectious Diseases, IRCCS Scientific Institute San Raffaele, 20132 Milan, Italy.

出版信息

Int J Mol Sci. 2020 Dec 25;22(1):150. doi: 10.3390/ijms22010150.

DOI:10.3390/ijms22010150
PMID:33375697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7795188/
Abstract

Preclinical models for the definition of anti-cancer drug safety and efficacy are constantly evolving [...].

摘要

癌症药物安全性和疗效的临床前模型不断发展演变。

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Rapid Clearing for High Resolution 3D Imaging of Ex Vivo Pancreatic Cancer Spheroids.快速清除用于离体胰腺癌球体的高分辨率 3D 成像。
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Astrocytes Decreased the Sensitivity of Glioblastoma Cells to Temozolomide and Bay 11-7082.星形胶质细胞降低胶质母细胞瘤细胞对替莫唑胺和 Bay 11-7082 的敏感性。
Int J Mol Sci. 2020 Sep 28;21(19):7154. doi: 10.3390/ijms21197154.
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Three-Dimensional Cell Cultures as an In Vitro Tool for Prostate Cancer Modeling and Drug Discovery.三维细胞培养作为前列腺癌建模和药物发现的体外工具。
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