接种麻疹、腮腺炎、风疹疫苗后出现严重免疫性血小板减少症并快速康复：一例报告及文献综述
Severe Immune Thrombocytopenia Following MMR Vaccination with Rapid Recovery: A Case Report and Review of Literature.
作者信息
Akbik Majd, Naddeh Dima, Ashour Anas A, Ashour Azzam
机构信息
Al-Thumama Health Center, Primary Health Care Corporation, Doha 26555, Qatar.
Muaither Health Center, Primary Health Care Corporation, Doha 26555, Qatar.
出版信息
Int Med Case Rep J. 2020 Dec 15;13:697-699. doi: 10.2147/IMCRJ.S286335. eCollection 2020.
Immune thrombocytopenia (ITP) is an autoimmune disease that occurs following viral illnesses and may also infrequently occur after measles, mumps, and rubella (MMR) vaccination. ITP typically presents with the sudden appearance of a petechial rash, bruising, and/or bleeding in an otherwise healthy-appearing child. However, ITP following MMR vaccine does not commonly cause severely depleted platelets. We report a case of ITP after MMR vaccination in a 13-month-old baby boy, who presented with petechial rash all over his body. The child had severe thrombocytopenia but was successfully treated with a single dose of intravenous immunoglobulin without complications. The study highlights that ITP post-MMR vaccine is an easily treatable condition.
免疫性血小板减少症（ITP）是一种在病毒感染后发生的自身免疫性疾病，也可能偶尔在麻疹、腮腺炎和风疹（MMR）疫苗接种后出现。ITP通常表现为在外表健康的儿童身上突然出现瘀点皮疹、瘀伤和/或出血。然而，MMR疫苗接种后的ITP通常不会导致血小板严重减少。我们报告一例13个月大男婴在接种MMR疫苗后发生ITP的病例，该患儿全身出现瘀点皮疹。患儿有严重血小板减少症，但通过单剂量静脉注射免疫球蛋白成功治愈，无并发症。该研究强调，MMR疫苗接种后发生的ITP是一种易于治疗的病症。
Zotero 插件