Ouenzar B, Agoutin B, Reinisch F, Weill D, Perin F, Keith G, Heyman T
Institut Curie, Section Biologie, Centre Universitaire, Orsay, France.
Biochem Biophys Res Commun. 1988 Jan 15;150(1):148-55. doi: 10.1016/0006-291x(88)90498-6.
The relation between codon usage and tRNA content for proline and glycine, the major constituents of collagen, was studied in two tissues: the magnum of laying hen oviduct and the leg tendons of chick embryo where collagen is produced. Although the relative contents of tRNA(GCCGly) and tRNA(IGGPro) in tendons, as compared to magnum indicate a specialization of the tRNA population for collagen synthesis, the distribution of the preponderant codons in collagen mRNA is correlated but at a lesser extent to that of their cognate tRNAs.
